Idiopathic pulmonary fibrosis

TE King, A Pardo, M Selman - The Lancet, 2011 - thelancet.com
Idiopathic pulmonary fibrosis is a devastating, age-related lung disease of unknown cause
that has few treatment options. This disease was once thought to be a chronic inflammatory …

Idiopathic pulmonary fibrosis

L Richeldi, HR Collard, MG Jones - The Lancet, 2017 - thelancet.com
Idiopathic pulmonary fibrosis is a prototype of chronic, progressive, and fibrotic lung disease.
Healthy tissue is replaced by altered extracellular matrix and alveolar architecture is …

New cellular and molecular mechanisms of lung injury and fibrosis in idiopathic pulmonary fibrosis

IE Fernandez, O Eickelberg - The Lancet, 2012 - thelancet.com
Idiopathic pulmonary fibrosis is a serious and progressive chronic lung disease that is
characterised by altered cellular composition and homoeostasis in the peripheral lung …

Time for a change: is idiopathic pulmonary fibrosis still idiopathic and only fibrotic?

PJ Wolters, TS Blackwell, O Eickelberg… - The Lancet …, 2018 - thelancet.com
Idiopathic pulmonary fibrosis (IPF) is a progressive, irreversible, and typically fatal lung
disease characterised by subpleural fibrosis, subepithelial fibroblast foci, and microscopic …

[PDF][PDF] Beyond epithelial damage: vascular and endothelial contributions to idiopathic pulmonary fibrosis

J May, JA Mitchell, RG Jenkins - Journal of Clinical …, 2023 - Am Soc Clin Investig
Idiopathic pulmonary fibrosis (IPF) is a progressive scarring disease of the lung with poor
survival. The incidence and mortality of IPF are rising, but treatment remains limited …

Idiopathic pulmonary fibrosis: pathogenesis and therapeutic approaches

M Selman, VJ Thannickal, A Pardo, DA Zisman… - Drugs, 2004 - Springer
Idiopathic pulmonary fibrosis (IPF), also termed cryptogenic fibrosing alveolitis, is a
clinicopathological syndrome characterised by cough, exertional dyspneoa, basilar crackles …

Idiopathic pulmonary fibrosis: new insights in its pathogenesis

A Pardo, M Selman - The international journal of biochemistry & cell biology, 2002 - Elsevier
Idiopathic pulmonary fibrosis (IPF) is a unique type of chronic fibrosing lung disease of
unknown etiology. The sequence of the pathogenic mechanisms is unknown, but the …

What have we learned from basic science studies on idiopathic pulmonary fibrosis?

T Yanagihara, S Sato, C Upagupta… - European Respiratory …, 2019 - Eur Respiratory Soc
Idiopathic pulmonary fibrosis is a fatal age-related lung disease characterised by
progressive and irreversible scarring of the lung. Although the details are not fully …

Pathogenic mechanisms underlying idiopathic pulmonary fibrosis

BJ Moss, SW Ryter, IO Rosas - Annual Review of Pathology …, 2022 - annualreviews.org
The pathogenesis of idiopathic pulmonary fibrosis (IPF) involves a complex interplay of cell
types and signaling pathways. Recurrent alveolar epithelial cell (AEC) injury may occur in …

Idiopathic pulmonary fibrosis: a disorder of epithelial cell dysfunction

DF Zoz, WE Lawson, TS Blackwell - The American journal of the medical …, 2011 - Elsevier
Idiopathic pulmonary fibrosis (IPF) is characterized by progressive dyspnea, interstitial
infiltrates in lung parenchyma and restriction on pulmonary function testing. IPF is the most …