Current and common definitions of treatment-resistant depression: findings from a systematic review and qualitative interviews

S Brown, K Rittenbach, S Cheung… - The Canadian …, 2019 - journals.sagepub.com
Objective: No universal definition for treatment-resistant depression (TRD) exists. This lack
of consensus reduces the generalizability of study findings and limits the ability to study …

[PDF][PDF] Defining treatment-resistant depression: a comprehensive review of the literature

K Trevino, SM McClintock, NMD Fischer, A Vora… - , 26, 3, 2014 - researchgate.net
BACKGROUND: Despite the common occurrence and debilitating nature of treatment-
resistant depression (TRD), currently there is no universally accepted definition for TRD …

[HTML][HTML] Definition of treatment-resistant depression–Asia Pacific perspectives

CH Ng, T Kato, C Han, G Wang, M Trivedi… - Journal of affective …, 2019 - Elsevier
Background The lack of uniformity in the definition of treatment resistant depression (TRD)
within the Asia-Pacific (APAC) region may have implications for patient management. We …

What happens to patients with treatment-resistant depression? A systematic review of medium to long term outcome studies

A Fekadu, SC Wooderson, K Markopoulo… - Journal of affective …, 2009 - Elsevier
BACKGROUND: Treatment-resistant depression (TRD) is relatively common and accounts
for a large proportion of the overall burden caused by depression. We conducted a …

Treatment-resistant depression

D Souery, GI Papakostas, MH Trivedi - Journal of Clinical …, 2006 - psychiatrist.com
Treatment-resistant depression (TRD) is a common clinical occurrence among patients
treated for major depressive disorder. However, a clear consensus regarding the criteria …

Defining treatment‐resistant depression

BN Gaynes, L Lux, G Gartlehner, G Asher… - Depression and …, 2020 - Wiley Online Library
Background Varying conceptualizations of treatment‐resistant depression (TRD) have made
translating research findings or systematic reviews into clinical practice guidelines …

Definition, assessment, and staging of treatment—resistant refractory major depression: a review of current concepts and methods

MT Berlim, G Turecki - The Canadian Journal of Psychiatry, 2007 - journals.sagepub.com
Objective: Up to 15% of depression patients eventually present with treatment-resistant or
refractory depression (TRD), a condition that causes significant social and economic …

Treatment‐resistant depression: definition, prevalence, detection, management, and investigational interventions

RS McIntyre, M Alsuwaidan, BT Baune, M Berk… - World …, 2023 - Wiley Online Library
Treatment‐resistant depression (TRD) is common and associated with multiple serious
public health implications. A consensus definition of TRD with demonstrated predictive utility …

Treatment‐resistant depression: resistant to definition?

GS Malhi, GB Parker, J Crawford… - Acta Psychiatrica …, 2005 - Wiley Online Library
Objective: To better define treatment‐resistant depression (TRD) so as to assist clinical
management and refine treatment guidelines. Method: In this study, we examine a broad …

[HTML][HTML] Definition of treatment-resistant depression in the Medicare population

BN Gaynes, G Asher, G Gartlehner, V Hoffman, J Green… - 2018 - europepmc.org
Objectives To inform future discussions and decisions about how to define treatment-
resistant depression (TRD) and specify the important outcomes measured in research …