Antibiotic resistance in Pseudomonas aeruginosa biofilms: towards the development of novel anti-biofilm therapies

PK Taylor, ATY Yeung, REW Hancock - Journal of biotechnology, 2014 - Elsevier
The growth of bacteria as structured aggregates termed biofilms leads to their protection
from harsh environmental conditions such as physical and chemical stresses, shearing …

[HTML][HTML] Clinical Impact of Antibiotics for the Treatment of Pseudomonas aeruginosa Biofilm Infections

E Olivares, S Badel-Berchoux, C Provot… - Frontiers in …, 2020 - frontiersin.org
Bacterial biofilms are highly recalcitrant to antibiotic therapies due to multiple tolerance
mechanisms. The involvement of Pseudomonas aeruginosa in a wide range of biofilm …

Pseudomonas aeruginosa biofilm infections: From molecular biofilm biology to new treatment possibilities

T Tolker‐Nielsen - Apmis, 2014 - Wiley Online Library
Bacteria in natural, industrial and clinical settings predominantly live in biofilms, ie, sessile
structured microbial communities encased in self‐produced extracellular matrix material …

[HTML][HTML] Tolerance and Resistance of Pseudomonas aeruginosa Biofilms to Antimicrobial Agents—How P. aeruginosa Can Escape Antibiotics

O Ciofu, T Tolker-Nielsen - Frontiers in microbiology, 2019 - frontiersin.org
Pseudomonas aeruginosa is one of the six bacterial pathogens, Enterococcus faecium,
Staphylococcus aureus, Klebsiella pneumoniae, Acinetobacter baumannii, Pseudomonas …

[HTML][HTML] Tolerance and Persistence of Pseudomonas aeruginosa in Biofilms Exposed to Antibiotics: Molecular Mechanisms, Antibiotic Strategies and Therapeutic …

A Soares, K Alexandre, M Etienne - Frontiers in microbiology, 2020 - frontiersin.org
Pseudomonas aeruginosa biofilm-related infections are difficult to treat with antibiotics.
Along the different layers of the biofilm, the P. aeruginosa population is heterogeneous …

[HTML][HTML] Pseudomonas aeruginosa Biofilm Formation and Its Control

A Vetrivel, M Ramasamy, P Vetrivel, S Natchimuthu… - Biologics, 2021 - mdpi.com
Microbes are hardly seen as planktonic species and are most commonly found as biofilm
communities in cases of chronic infections. Biofilms are regarded as a biological condition …

[HTML][HTML] Treatment of Pseudomonas aeruginosa infectious biofilms: Challenges and strategies

R Yin, J Cheng, J Wang, P Li, J Lin - Frontiers in Microbiology, 2022 - frontiersin.org
Pseudomonas aeruginosa, a Gram-negative bacterium, is one of the major pathogens
implicated in human opportunistic infection and a common cause of clinically persistent …

An explorative review on advanced approaches to overcome bacterial resistance by curbing bacterial biofilm formation

F Mohamad, RR Alzahrani, A Alsaadi… - Infection and Drug …, 2023 - Taylor & Francis
The continuous emergence of multidrug-resistant pathogens evoked the development of
innovative approaches targeting virulence factors unique to their pathogenic cascade …

[HTML][HTML] Biofilm Matrix and Its Regulation in Pseudomonas aeruginosa

Q Wei, LZ Ma - International journal of molecular sciences, 2013 - mdpi.com
Biofilms are communities of microorganisms embedded in extracellular polymeric
substances (EPS) matrix. Bacteria in biofilms demonstrate distinct features from their free …

[HTML][HTML] Antimicrobial resistance of Pseudomonas aeruginosa biofilms

E Drenkard - Microbes and infection, 2003 - Elsevier
Resistance to antimicrobial agents is the most important feature of biofilm infections. As a
result, infections caused by bacterial biofilms are persistent and very difficult to eradicate …