Potential effects of vildagliptin on biomarkers associated with prothrombosis in diabetes mellitus

S Khan, S Khan, BP Panda, M Akhtar… - Expert Opinion on …, 2015 - Taylor & Francis
Objective: Diabetes mellitus (DM) is one of the risks linked with susceptibility of thrombosis.
We tried to inspect the effect of a novel oral antidiabetic agent, vildagliptin, in preventing …

Effects of pioglitazone and vildagliptin on coagulation cascade in diabetes mellitus–targeting thrombogenesis

S Khan, S Khan, M Imran, KK Pillai… - Expert opinion on …, 2013 - Taylor & Francis
Introduction: Type 2 diabetes mellitus (T2DM) is intricately allied with an increased risk of
atherothrombotic disease. Thrombosis is the cause of mortality in 80% of patients with …

[HTML][HTML] Vasculoprotective effects of vildagliptin. Focus on atherogenesis

M Wiciński, K Górski, E Wódkiewicz, M Walczak… - International journal of …, 2020 - mdpi.com
Vildagliptin is a representative of Dipeptidyl Peptidase-4 (DPP-4) inhibitors,
antihyperglycemic drugs, approved for use as monotherapy and combination therapy in type …

[HTML][HTML] Effects of a vildagliptin/metformin combination on markers of atherosclerosis, thrombosis, and inflammation in diabetic patients with coronary artery disease

R Klempfner, J Leor, A Tenenbaum, EZ Fisman… - Cardiovascular …, 2012 - Springer
Background Diabetic patients present with an accelerated atherosclerotic process and an
increased risk for future cardiovascular events. In addition to the risk imposed by the disease …

Beneficial effects of vildagliptin on metabolic parameters in patients with type 2 diabetes

M Shimodaira, T Niwa, K Nakajima… - … , Metabolic & Immune …, 2015 - ingentaconnect.com
Blood pressure and lipid profile are important determinants of cardiovascular risk in patients
with type 2 diabetes mellitus (T2DM). To identify the pleiotropic effects of vildagliptin other …

Comparative clinical study evaluating the effect of adding Vildagliptin versus Glimepiride to ongoing Metformin therapy on diabetic patients with symptomatic coronary …

R Werida, M Kabel, G Omran, A Shokry… - diabetes research and …, 2020 - Elsevier
Abstract Background and Objective Cardiovascular diseases (CVDs) remain the most
identified cause of death in patients with diabetes mellitus (DM). This study aimed to …

Effect of the novel oral dipeptidyl peptidase IV inhibitor vildagliptin on the pharmacokinetics and pharmacodynamics of warfarin in healthy subjects

YL He, R Sabo, GJ Riviere, G Sunkara… - … medical research and …, 2007 - Taylor & Francis
Objective: Vildagliptin is a potent and selective dipeptidyl peptidase‑IV (DPP‑4) inhibitor that
improves glycemic control in patients with type 2 diabetes by increasing alpha and beta-cell …

Vildagliptin inhibits oxidative stress and vascular damage in streptozotocin-induced diabetic rats

S Maeda, T Matsui… - International …, 2012 - internationaljournalofcardiology.com
Glucagon-like peptide-1 (GLP-1), a gut hormone secreted from L cells in the intestine in
response to food intake, not only augments glucosedependent insulin secretion from …

The role of vildagliptin in treating hypertension through modulating serum VEGF in diabetic hypertensive patients

AR El-Naggar, D Zaafar, M Elyamany… - Journal of …, 2019 - journals.sagepub.com
Background: Several trials have reported that dipeptidyl peptidase-4 (DPP-4) inhibitors are
used to improve endothelial function in addition to treating type 2 diabetes (T2DM). The …

Vildagliptin reduces plasma stromal cell‐derived factor‐1α in patients with type 2 diabetes compared with glimepiride

KS Park, SH Kwak, YM Cho, KS Park… - Journal of Diabetes …, 2017 - Wiley Online Library
Abstract Aims/Introduction Dipeptidyl peptidase‐4 inhibitors might have pleiotropic
protective effects on cardiovascular disease (CVD), in contrast to sulfonylureas. Therefore …