Effect of tocilizumab on clinical outcomes at 15 days in patients with severe or critical coronavirus disease 2019: randomised controlled trial
VC Veiga, JAGG Prats, DLC Farias, RG Rosa… - bmj, 2021 - bmj.com
Objective To determine whether tocilizumab improves clinical outcomes for patients with
severe or critical coronavirus disease 2019 (covid-19). Design Randomised, open label trial …
severe or critical coronavirus disease 2019 (covid-19). Design Randomised, open label trial …
[HTML][HTML] The effect of tocilizumab on mortality in hospitalized patients with COVID-19: a meta-analysis of randomized controlled trials
Objective We aimed to perform a meta-analysis of randomized controlled trials (RCTs) to
summarize the overall effect of tocilizumab on the risk of mortality among patients with …
summarize the overall effect of tocilizumab on the risk of mortality among patients with …
[HTML][HTML] Use of tocilizumab in COVID-19: a systematic review and meta-analysis of current evidence
S Kotak, M Khatri, M Malik, M Malik, W Hassan… - Cureus, 2020 - ncbi.nlm.nih.gov
Materials and methods Online databases (PubMed and Cochrane) were searched until
June 29, 2020, for original articles investigating the immunological response in COVID-19 …
June 29, 2020, for original articles investigating the immunological response in COVID-19 …
[HTML][HTML] Effect of tocilizumab in hospitalized patients with severe COVID-19 pneumonia: a case-control cohort study
B Rossi, LS Nguyen, P Zimmermann, F Boucenna… - Pharmaceuticals, 2020 - mdpi.com
Tocilizumab, an anti-interleukin-6 receptor, administrated during the right timeframe may be
beneficial against coronavirus-disease-2019 (COVID-19) pneumonia. All patients admitted …
beneficial against coronavirus-disease-2019 (COVID-19) pneumonia. All patients admitted …
Tocilizumab in patients hospitalized with COVID-19 pneumonia: systematic review and meta-analysis of randomized controlled trials
S Gupta, RP Padappayil, A Bansal… - Journal of …, 2022 - journals.sagepub.com
Tocilizumab is an interleukin receptor inhibitor that has been used in patients with COVID-19
pneumonia. There are recent randomized controlled trials (RCTs) that evaluated the efficacy …
pneumonia. There are recent randomized controlled trials (RCTs) that evaluated the efficacy …
[HTML][HTML] Efficacy and safety of tocilizumab in COVID-19 patients: a living systematic review and meta-analysis, first update
IM Tleyjeh, Z Kashour, M Riaz, L Hassett… - Clinical Microbiology …, 2021 - Elsevier
Objectives Cytokine release syndrome with elevated interleukin-6 (IL-6) levels is associated
with multiorgan damage and death in severe coronavirus disease 2019 (COVID-19). Our …
with multiorgan damage and death in severe coronavirus disease 2019 (COVID-19). Our …
[HTML][HTML] Efficacy and safety of tocilizumab in COVID-19 patients: a living systematic review and meta-analysis
IM Tleyjeh, Z Kashour, M Damlaj, M Riaz… - Clinical Microbiology …, 2021 - Elsevier
Objectives Cytokine release syndrome with elevated interleukin-6 (IL-6) levels is associated
with multiorgan damage and death in severe coronavirus disease 2019 (COVID-19). Our …
with multiorgan damage and death in severe coronavirus disease 2019 (COVID-19). Our …
[HTML][HTML] Tocilizumab in the treatment of critical COVID-19 pneumonia: A retrospective cohort study of mechanically ventilated patients
MJ Fisher, LAM Raymundo, M Monteforte… - International Journal of …, 2021 - Elsevier
Objectives The purpose of this study is to evaluate clinical outcomes in patients with critical
COVID-19 pneumonia requiring invasive mechanical ventilation who were treated with …
COVID-19 pneumonia requiring invasive mechanical ventilation who were treated with …
Efficacy and safety of tocilizumab versus standard care/placebo in patients with COVID‐19; a systematic review and meta‐analysis of randomized clinical trials
Aims Tocilizumab has emerged as an important therapy in treating patients with coronavirus
disease (COVID‐19). Our purpose was to evaluate the efficacy and safety of tocilizumab …
disease (COVID‐19). Our purpose was to evaluate the efficacy and safety of tocilizumab …
[HTML][HTML] Tocilizumab in patients with severe COVID-19: a retrospective cohort study
G Guaraldi, M Meschiari, A Cozzi-Lepri… - The Lancet …, 2020 - thelancet.com
Background No therapy is approved for COVID-19 pneumonia. The aim of this study was to
assess the role of tocilizumab in reducing the risk of invasive mechanical ventilation and …
assess the role of tocilizumab in reducing the risk of invasive mechanical ventilation and …