Gene Expression Profiling of Human Oocytes Developed and Matured In Vivo or In Vitro

I Virant-Klun, K Knez, T Tomazevic… - BioMed research …, 2013 - Wiley Online Library
The quality of the human oocyte determines the success of fertilization and affects the
consequent embryo development, pregnancy and birth; it therefore serves as a basis for …

Human oocyte maturation in vitro is improved by co-culture with cumulus cells from mature oocytes

I Virant-Klun, C Bauer, A Ståhlberg, M Kubista… - Reproductive …, 2018 - Elsevier
The conventional method of human oocyte maturation in vitro in the presence of
gonadotrophins continues to be a relatively low-success procedure in the assisted …

The study of mammalian oocyte competence by transcriptome analysis: progress and challenges

R Labrecque, MA Sirard - Molecular human reproduction, 2014 - academic.oup.com
Various morphological and cytological traits of oocytes and their surrounding cumulus cells
may be used to select oocytes for assisted reproduction. However, even with careful …

[HTML][HTML] In vitro generation of oocytes from ovarian stem cells (OSCs): in search of major evidence

E Silvestris, S D'Oronzo, P Cafforio… - International journal of …, 2019 - mdpi.com
The existence of ovarian stem cells (OSCs) in women as well as their physiological role in
post-menopausal age are disputed. However, accumulating evidence demonstrated that …

In vitro differentiation of human oocyte-like cells from oogonial stem cells: single-cell isolation and molecular characterization

E Silvestris, P Cafforio, S D'oronzo, C Felici… - Human …, 2018 - academic.oup.com
STUDY QUESTION Are the large cells derived from cultured DEAD box polypeptide 4
(DDX4)-positive oogonial stem cells (OSCs), isolated from the ovarian cortex of non …

[HTML][HTML] Portrait of an oocyte: our obscure origin

R Gosden, B Lee - The Journal of clinical investigation, 2010 - Am Soc Clin Investig
Oocytes play a pivotal role in the cycle of human life. As we discuss here, after emerging
from germline stem cells in the fetus, they grow in a follicular niche in which development is …

Gene expression profiling of human oocytes following in vivo or in vitro maturation

GM Jones, DS Cram, B Song, MC Magli… - Human …, 2008 - academic.oup.com
BACKGROUND Immature human oocytes matured in vitro, particularly those from
gonadotrophin stimulated ovaries, are developmentally incompetent when compared with …

Morphological criteria of oocyte quality

K Lasienë, A Vitkus, A Valanèiûtë, V Lasys - Medicina, 2009 - mdpi.com
In vitro fertilization technology consists of the selection and fertilization of oocytes, the
production and transplantation of embryos to recipients. The quality of oocytes has a direct …

Postnatal oogenesis in humans: a review of recent findings

I Virant-Klun - Stem cells and cloning: advances and applications, 2015 - Taylor & Francis
In spite of generally accepted dogma that the total number of follicles and oocytes is
established in human ovaries during the fetal period of life rather than forming de novo in …

Identifying new human oocyte marker genes: a microarray approach

S Gasca, F Pellestor, S Assou, V Loup… - Reproductive …, 2007 - Elsevier
The efficacy of classical IVF techniques is still impaired by poor implantation and pregnancy
rates after embryo transfer. This is mainly due to a lack of reliable criteria for the selection of …