In a double-masked, 3-month clinical study the ocular hypotensive effects of diacetyl nadolol
(DAN), timolol, and nadolol were compared. When applied topically to the eyes of …

Forty six normal volunteers were randomly assigned in double-blind fashion to once daily
orally administered nadolol 10, 20, 40, or 80 mg for five days. Significant and dose related …

• On topical application to rabbit eyes, the diacetate ester of nadolol was more easily
absorbed into ocular tissue than nadolol and was enzymatically hydrolyzed to nadolol within …

Oral atenolol (25 mg twice daily and 50 mg and 100 mg once daily) and placebo were tested
as additional therapy in a double-masked, randomised, cross-over study. Twenty-four …

We compared the effects of oral nadolol 20 mg once daily and topical timolol 0.25% twice
daily on the intraocular pressures of 22 glaucoma suspects, in a 12 week double-masked …

The 12-hour control of intraocular pressure obtained with 10 and 20 mg of nadolol twice
daily was studied in a placebo-controlled trial. In this ten-week study involving 17 patients a …

The effect of long-term application of 4% atenolol eye drops has been studied in patients
with either glaucoma or ocular hypertension. In some patients who show a good initial …

In a controlled double-blind cross-over trial in 10 patients comprising six with open-angle
glaucoma, three with closed-angle glaucoma, and one with ocular hypertension, a single …

One of the most intriguing and daily recurring problems in the ophthalmological practice is
glaucoma; for as we know every glaucoma patient has to face the fact their eye sight is …

Atenolol (Tenormin or ICI 66082) is a new beta-adrenergic blocking drug, unique in being
cardio-selective and in having no intrinsic sympathomimetic or membrane activity. In a …