Decreased syngeneic mixed lymphocyte reaction in autoimmune susceptible mice

JT Hom, N Talal - Scandinavian Journal of Immunology, 1982 - Wiley Online Library
The syngeneic mixed lymphocyte reaction (SMLR) is a proliferative response mediated by
murine splenic thymus‐derived (T) lymphocytes after stimulation by syngeneic non‐T cells …

Syngeneic mixed lymphocyte reaction in mice: strain distribution, kinetics, participating cells, and absence in NZB mice

J Bruce Smith, RD Pasternak - The Journal of Immunology, 1978 - journals.aai.org
Co-culture of mouse spleen nonadherent (T-enriched) cells with mitomycin C-treated
unfractionated syngeneic spleen cells resulted in increased DNA synthesis in the …

Studies on the syngeneic mixed lymphocyte reaction. II. Decline in he syngeneic mixed lymphocyte reaction with age.

JK Gutowski, ME Weksler - Immunology, 1982 - ncbi.nlm.nih.gov
The syngeneic mixed lymphocyte reaction (SMLR) is the proliferative response of T
lymphocytes cultured with syngeneic non-T lymphocytes. In previous studies, we found that …

Studies on the syngeneic mixed lymphocyte reaction. I. The ontogeny of the syngeneic mixed lymphocyte reaction in mice.

JK Gutowski, ME Weksler - Immunology, 1982 - ncbi.nlm.nih.gov
The syngeneic mixed lymphocyte reaction (SMLR) is the proliferative response of T
lymphocytes cultured with syngeneic non-T lymphocytes. The ontogenic development of the …

Comparative analysis of splenic cell proliferation induced by interleukin 3 and by syngeneic accessory cells (syngeneic mixed leukocyte reaction): evidence that …

AC Bonomo, MC El-Cheikh, R Borojevic… - Cellular …, 1990 - Elsevier
Murine syngeneic mixed leukocyte reaction (SMLR) was studied under totally autologous
culture conditions using syngeneic normal mouse serum in the culture. SMLR was detected …

The developmental biology of the syngeneic mixed lymphocyte reaction.

CE Moody, PB Hausman, JK Gutowski… - Behring Institute …, 1983 - europepmc.org
The syngeneic mixed lymphocyte reaction (SMLR) is the proliferative response of T
lymphocytes cultured with non-T lymphocytes. Normal mouse serum supports proliferative …

[引用][C] Helper cells in the autologous mixed lymphocyte reaction. II. Age-related helper defect for generation of TNP-self cytotoxic cells in NZB mice.

JA Wolos, JB Smith - Journal of immunology (Baltimore, Md.: 1950), 1982 - journals.aai.org
The autologous mixed lymphocyte reaction (AMLR) in mice measures the proliferative
response of T cells to I region determinants on syngeneic spleen cells. Cytotoxic cells …

Evidence for major alterations in the thymocyte subpopulations in murine models of autoimmune diseases

VN Kakkanaiah, RH Pyle, M Nagarkatti… - Journal of …, 1990 - Elsevier
Thymocytes can be divided into four major subpopulations: CD4+ CD8+(double-positive),
CD4− CD8−(double-negative), CD4+ CD8−(CD4+) and CD4− CD8+(CD8+) cells. Recent …

The relationship between the defect in the syngeneic mixed lymphocyte reaction and thymic abnormality in New Zealand mice.

M Minoda, S Senda, A Horiuchi - Journal of clinical & laboratory …, 1987 - europepmc.org
Whether a defect the syngeneic mixed lymphocyte reaction (SMLR) is caused by an
abnormality in the recognition of autoantigen (Ia antigen) by T cells or by an abnormality in …

Selective stimulation by B lymphocytes in the syngeneic mixed lymphocyte reaction

H Von Boehmer - European Journal of Immunology, 1974 - Wiley Online Library
T and B lymphocytes from spleen and thoracic duct have been separated by preparative
electrophoresis and their ability to stimulate syngeneic and allogeneic thymic cells in mixed …