Carcinoma of the colon is common and its incidence varies according to the geographical
location and dietary habits. The aims of this paper are, first, to review the current …

In recent years, several lines of epidemiologic, clinical and experimental evidences have
been reported showing that estrogen hormones may be involved in malignant colorectal …

Colorectal cancer is the third leading cause of cancer death in women. Studies on the
potential protective effect of postmenopausal hormone replacement on the incidence of …

Exogenous sex hormones seem to play a role in colorectal carcinogenesis. Little is known
about the influence of different types or durations of postmenopausal hormone therapy (HT) …

Mortality rates for colorectal cancer in many developed countries have declined in women
more than in men. Possible explanations of the sex differentials in colorectal cancer mainly …

Background: The results of several recent epidemiologic studies suggest that estrogen
replacement therapy (ERT) in postmenopausal women may decrease their risk of …

Aim The role of oestrogen metabolism and action in colorectal cancer (CRC) is
controversial. An extensive review of the current literature, encompassing epidemiological …

BACKGROUND The preponderance of observational studies describe an association
between the use of estrogen alone and a lower incidence of colorectal cancer. In contrast …

Observational epidemiological studies and randomized trials have reported a protective
effect of estrogen and progestin therapy (EPT) on the risk of colorectal cancer but the …

Purpose Postmenopausal estrogen use has been shown to decrease the incidence of
colorectal cancer, but there is limited information regarding the effect of estrogen use on …