Abstract Background/Aims: Several clinical, epidemiological, and animal studies indicate
that nonsteroidal anti-inflammatory drugs (NSAIDs) may alter the incidence of colorectal …

OBJECTIVES: Subjects in the Prevention of Colorectal Sporadic Adenomatous Polyps
(PreSAP) trial (PRESAP/NCT00141193/www. clinicaltrials. gov) were studied to determine …

Background Beneficial effects of aspirin and non-aspirin nonsteroidal anti-inflammatory
drugs (NSAIDs) against recurrent colorectal adenomas have been documented in …

Background Patients with familial adenomatous polyposis have a nearly 100 percent risk of
colorectal cancer. In this disease, the chemopreventive effects of nonsteroidal …

The tumor-suppressive effects of nonsteroidal antiinflammatory drugs (NSAIDs) have been
suggested to be due to a reduction in cyclooxygenase (COX)-2 activity, although the effects …

Epidemiological, clinical and animal studies indicate non-steroidal anti-inflammatory drugs
(NSAIDs) to be chemopreventive for colorectal cancer. The best established target for …

Use of aspirin and other nonsteroidal anti-inflammatory drugs (NSAIDs) has been
associated with reduced risk of colorectal cancer. Moreover, the NSAID sulindac reduces the …

Colorectal cancer is the second leading cause of death from cancer in the United States.
Differences in dietary habits and lifestyles among populations in different geographic …

Background Selective cyclooxygenase inhibitors may retard the progression of cancer, but
they have enhanced thrombotic potential. We report on cardiovascular adverse events in …

PURPOSE: A systematic review was conducted to determine the effect of nonsteroidal anti-
inflammatory drugs for the prevention or regression of colorectal adenomas and cancer …