[HTML][HTML] Frequency of EGFR and KRAS mutations in lung adenocarcinomas in African Americans

JM Reinersman, ML Johnson, GJ Riely… - Journal of Thoracic …, 2011 - Elsevier
Introduction: The detection of mutations in the epidermal growth factor receptor (EGFR)
gene, which predict sensitivity to treatment with EGFR tyrosine kinase inhibitors, represents …

[HTML][HTML] Mutational analysis in cytological specimens of advanced lung adenocarcinoma: a sensitive method for molecular diagnosis

L Boldrini, S Gisfredi, S Ursino, T Camacci… - Journal of Thoracic …, 2007 - Elsevier
Introduction The discovery that somatic mutations in the epidermal growth factor receptor
(EGFR) gene are associated with sensitivity to the EGFR tyrosine kinase inhibitors (TKIs) in …

[HTML][HTML] Clinicopathologic characteristics of the EGFR gene mutation in non–small cell lung cancer

AS Tsao, XM Tang, B Sabloff, L Xiao… - Journal of Thoracic …, 2006 - Elsevier
Background The authors sought to define clinicopathologic features associated with
mutations of the epidermal growth factor receptor (EGFR) gene in non–small cell lung …

EGFR mutations in lung adenocarcinomas: clinical testing experience and relationship to EGFR gene copy number and immunohistochemical expression

AR Li, D Chitale, GJ Riely, W Pao, VA Miller… - The Journal of Molecular …, 2008 - Elsevier
Lung adenocarcinomas responsive to epidermal growth factor receptor (EGFR) tyrosine
kinase inhibitors possess EGFR mutations and often increased EGFR copy number. We …

[HTML][HTML] A prospective, molecular epidemiology study of EGFR mutations in Asian patients with advanced non–small-cell lung cancer of adenocarcinoma histology …

Y Shi, JSK Au, S Thongprasert, S Srinivasan… - Journal of thoracic …, 2014 - Elsevier
Introduction: PIONEER (NCT01185314) was a prospective, multinational, epidemiological
study of epidermal growth factor receptor (EGFR) mutations in patients from Asia with newly …

EGFR and KRAS mutations in lung carcinomas in the Dutch population: increased EGFR mutation frequency in malignant pleural effusion of lung adenocarcinoma

AJJ Smits, JA Kummer, JWJ Hinrichs, GJM Herder… - Cellular oncology, 2012 - Springer
Background Frequencies of EGFR and KRAS mutations in non-small cell lung cancer
(NSCLC) have predominantly been determined in East Asian and North American …

[HTML][HTML] Updated frequency of EGFR and KRAS mutations in nonsmall-cell lung cancer in Latin America: the Latin-American Consortium for the Investigation of Lung …

O Arrieta, AF Cardona, C Martín, L Más-López… - Journal of Thoracic …, 2015 - Elsevier
Introduction Previously, we reported the frequency of epidermal growth factor receptor
(EGFR) and KRAS mutations in nonsmall-cell lung cancer (NSCLC) patients in Latin …

EGFR and KRAS mutations in lung carcinoma Molecular testing by using cytology specimens

S Billah, J Stewart, G Staerkel, S Chen… - Cancer …, 2011 - Wiley Online Library
BACKGROUND: The aim of this study was to validate clinical utilization of routinely prepared
cytology specimens for molecular testing to detect EGFR or KRAS mutations in lung cancer …

[HTML][HTML] Distinct epidemiology and clinical consequence of classic versus rare EGFR mutations in lung adenocarcinoma

Z Lohinai, MA Hoda, K Fabian, G Ostoros… - Journal of thoracic …, 2015 - Elsevier
Introduction Although classic sensitizing mutations of epidermal growth factor receptor
(EGFR) are positive predictive markers for EGFR tyrosine kinase inhibitors (TKIs) in lung …

[HTML][HTML] Frequency and type of epidermal growth factor receptor mutations in African Americans with non-small cell lung cancer

ML Cote, R Haddad, DJ Edwards, G Atikukke… - Journal of Thoracic …, 2011 - Elsevier
Background: Epidermal growth factor receptor (EGFR) mutations in non-small cell lung
cancer (NSCLC) predict response to tyrosine kinase inhibitors. Mutations occur more …