Correlation of EGFR Mutation Status With Predominant Histologic Subtype of Adenocarcinoma According to the New Lung Adenocarcinoma Classification of the …
C Villa, PT Cagle, M Johnson… - … of Pathology and …, 2014 - meridian.allenpress.com
Context.—Epidermal growth factor receptor (EGFR) mutations have been identified as
predictors of response to EGFR tyrosine kinase inhibitors in non–small cell lung cancer …
predictors of response to EGFR tyrosine kinase inhibitors in non–small cell lung cancer …
KRAS Mutation Is an Important Predictor of Resistance to Therapy with Epidermal Growth Factor Receptor Tyrosine Kinase Inhibitors in Non–Small-Cell Lung Cancer
E Massarelli, M Varella-Garcia, X Tang, AC Xavier… - Clinical cancer …, 2007 - AACR
Purpose: EGFR gene mutations and increased EGFR copy number have been associated
with favorable response to epidermal growth factor receptor (EGFR) tyrosine kinase …
with favorable response to epidermal growth factor receptor (EGFR) tyrosine kinase …
Identification of EGFR kinase domain mutations among lung cancer patients in China: implication for targeted cancer therapy
Lung cancer is one of the leading causes of death with one of the lowest survival rates.
However, a subset of lung cancer patients who are of Asian origin and carry somatic …
However, a subset of lung cancer patients who are of Asian origin and carry somatic …
Heterogeneous Distribution of EGFR Mutations Is Extremely Rare in Lung Adenocarcinoma
Purpose Some studies have shown that epidermal growth factor receptor (EGFR) mutations
can be heterogeneously distributed in individual tumors. In this study, we re-evaluated the …
can be heterogeneously distributed in individual tumors. In this study, we re-evaluated the …
Incidence of EGFR Exon 19 Deletions and L858R in Tumor Specimens From Men and Cigarette Smokers With Lung Adenocarcinomas
SP D'Angelo, MC Pietanza, ML Johnson… - Journal of clinical …, 2011 - ascopubs.org
Purpose EGFR mutations underlie the sensitivity of lung cancers to erlotinib and gefitinib
and can occur in any patient with this illness. Here we examine the frequency of EGFR …
and can occur in any patient with this illness. Here we examine the frequency of EGFR …
Frequency of and variables associated with the EGFR mutation and its subtypes
T Tanaka, M Matsuoka, A Sutani… - … journal of cancer, 2010 - Wiley Online Library
Mutation in the epidermal growth factor receptor (EGFR) is frequently seen in non‐small cell
lung cancers (NSCLCs), especially in Asian females with adenocarcinoma. The frequency of …
lung cancers (NSCLCs), especially in Asian females with adenocarcinoma. The frequency of …
[HTML][HTML] An alternative method for screening EGFR mutation using RFLP in non-small cell lung cancer patients
I Kawada, K Soejima, H Watanabe, I Nakachi… - Journal of Thoracic …, 2008 - Elsevier
Introduction Epidermal growth factor receptor (EGFR) mutations are strong determinants of
tumor response to EGFR tyrosine kinase inhibitors in non-small cell lung cancers (NSCLCs) …
tumor response to EGFR tyrosine kinase inhibitors in non-small cell lung cancers (NSCLCs) …
Role of EGFR mutations in lung cancers: prognosis and tumor chemosensitivity
K Suda, T Mitsudomi - Archives of toxicology, 2015 - Springer
Lung cancers with an epidermal growth factor receptor (EGFR) gene mutation account for~
40% of adenocarcinomas in East Asians and~ 15% of those in Caucasians and African …
40% of adenocarcinomas in East Asians and~ 15% of those in Caucasians and African …
Epidermal growth factor receptor mutations in non–small-cell lung cancer: Implications for treatment and tumor biology
PA Jänne, JA Engelman, BE Johnson - Journal of clinical oncology, 2005 - ascopubs.org
The epidermal growth factor receptor (EGFR) has emerged as an attractive therapeutic
target for patients with non–small-cell lung cancer (NSCLC). However, despite its almost …
target for patients with non–small-cell lung cancer (NSCLC). However, despite its almost …
Epidermal growth factor receptor and KRAS mutations in Brazilian lung cancer patients
CE Bacchi, H Ciol, EM Queiroga, LC Benine, LH Silva… - Clinics, 2012 - SciELO Brasil
OBJECTIVE: Epidermal growth factor receptor is involved in the pathogenesis of non-small
cell lung cancer and has recently emerged as an important target for molecular therapeutics …
cell lung cancer and has recently emerged as an important target for molecular therapeutics …