A safety update on sodium glucose co‐transporter 2 inhibitors

D Fitchett - Diabetes, Obesity and Metabolism, 2019 - Wiley Online Library
Sodium glucose co‐transporter 2 inhibitors (SGLT2is) are the first class of glucose lowering
agent to be shown to reduce cardiovascular events. They are generally well tolerated with …

Safety of sodium-glucose co-transporter 2 inhibitors

JB McGill, S Subramanian - The American Journal of Medicine, 2019 - Elsevier
Abstract Sodium-glucose co-transporter 2 (SGLT2) inhibitors have a well-defined safety
profile based on data obtained from numerous clinical trials, including cardiovascular …

Adverse events associated with sodium glucose co-transporter 2 inhibitors: an overview of quantitative systematic reviews

R Pelletier, K Ng, W Alkabbani… - … Advances in Drug …, 2021 - journals.sagepub.com
Background: Multiple published quantitative systematic reviews have reported on adverse
events associated with the use of sodium glucose co-transporter 2 (SGLT-2) inhibitors in …

Use of SGLT2 inhibitors in type 2 diabetes: weighing the risks and benefits

BC Lupsa, SE Inzucchi - Diabetologia, 2018 - Springer
Abstract Sodium–glucose cotransporter 2 (SGLT2) inhibitors belong to a novel class of
glucose-lowering medications that reduce plasma glucose concentrations by inhibiting …

Risk of amputation associated with sodium-glucose co-transporter 2 inhibitors: a meta-analysis of five randomized controlled trials

S Miyashita, T Kuno, H Takagi, T Sugiyama… - Diabetes Research and …, 2020 - Elsevier
Amputation has been known to be a rare adverse event of sodium glucose co-transporter-2
(SGLT2) inhibitors. It remains unclear whether the SGLT2 inhibitor as a class or specific …

Sodium-glucose co-transporter-2 inhibitors (SGLT2i) use and risk of amputation: an expert panel overview of the evidence

N Katsiki, G Dimitriadis, G Hahalis, N Papanas… - Metabolism, 2019 - Elsevier
Abstract Sodium-glucose co-transporter-2 inhibitors (SGLT2i) are oral antidiabetic agents
that exert their glucose-lowering effect by increasing renal excretion of glucose. These drugs …

Pharmacodynamics, efficacy and safety of sodium–glucose co-transporter type 2 (SGLT2) inhibitors for the treatment of type 2 diabetes mellitus

AJ Scheen - Drugs, 2015 - Springer
Inhibitors of sodium–glucose co-transporter type 2 (SGLT2) are proposed as a novel
approach for the management of type 2 diabetes mellitus (T2DM). Several compounds are …

Update review of the safety of sodium-glucose cotransporter 2 inhibitors for the treatment of patients with type 2 diabetes mellitus

CJ Carlson, ML Santamarina - Expert Opinion on Drug Safety, 2016 - Taylor & Francis
Introduction: The safety profile of sodium-glucose cotransporter 2 (SGLT2) inhibitors has
continued to evolve with the availability of data from clinical trial programs, post-marketing …

SGLT2 inhibitors: are they safe?

S Filippas-Ntekouan, TD Filippatos… - Postgraduate …, 2018 - Taylor & Francis
Sodium–glucose linked transporter type 2 (SGLT2) inhibitors are a relatively new class of
antidiabetic drugs with positive cardiovascular and kidney effects. The aim of this review is to …

Risks associated with SGLT2 inhibitors: an overview

M Singh, A Kumar - Current drug safety, 2018 - ingentaconnect.com
Background: Sodium glucose co-transport 2 inhibitors (SGLT2-i) are the new class of
antidiabetic medications which are recently approved (2013) by the Food and Drug …