Intermittent hypoxia: the culprit of oxidative stress, vascular inflammation and dyslipidemia in obstructive sleep apnea
L Lavie - Expert Review of Respiratory Medicine, 2008 - Taylor & Francis
Obstructive sleep apnea, a breathing disorder in sleep characterized by intermittent and
recurrent pauses in respiration, is also a major risk factor for cardiovascular morbidity and …
recurrent pauses in respiration, is also a major risk factor for cardiovascular morbidity and …
Insulin resistance is associated with tissue-specific regulation of HIF-1α and HIF-2α during mild chronic intermittent hypoxia
Chronic intermittent hypoxia (CIH) is a feature of obstructive sleep apnea (OSA). Whereas
clinical studies have demonstrated the association between OSA and insulin resistance, the …
clinical studies have demonstrated the association between OSA and insulin resistance, the …
[HTML][HTML] Validation of housekeeping genes in the brains of rats submitted to chronic intermittent hypoxia, a sleep apnea model
Obstructive sleep apnea (OSA) is a syndrome characterized by intermittent nocturnal
hypoxia, sleep fragmentation, hypercapnia and respiratory effort, and it has been associated …
hypoxia, sleep fragmentation, hypercapnia and respiratory effort, and it has been associated …
[HTML][HTML] Transcriptomics identify a unique intermittent hypoxia-mediated profile in obstructive sleep apnea
CD000072. 2. Kim T, Mcfee E, Olguin DO, Waber B, Pentland AS. Sociometric badges: using
sensor technology to capture new forms of collaboration. J Organ Behav 2012; 33: 412–427 …
sensor technology to capture new forms of collaboration. J Organ Behav 2012; 33: 412–427 …
[HTML][HTML] Effects of intermittent hypoxia on pulmonary vascular and systemic diseases
H Kimura, H Ota, Y Kimura, S Takasawa - International Journal of …, 2019 - mdpi.com
Obstructive sleep apnea (OSA) causes many systemic disorders via mechanisms related to
sympathetic nerve activation, systemic inflammation, and oxidative stress. OSA typically …
sympathetic nerve activation, systemic inflammation, and oxidative stress. OSA typically …
Transcriptional responses to intermittent hypoxia
J Nanduri, G Yuan, GK Kumar, GL Semenza… - Respiratory physiology …, 2008 - Elsevier
Recurrent apneas are characterized by transient repetitive cessations of breathing (two
breaths duration or longer) resulting in periodic decreases in arterial blood PO2 or chronic …
breaths duration or longer) resulting in periodic decreases in arterial blood PO2 or chronic …
Intermittent hypoxia in obstructive sleep apnoea mediates insulin resistance through adipose tissue inflammation
AM Murphy, A Thomas, SJ Crinion… - European …, 2017 - Eur Respiratory Soc
Obstructive sleep apnoea (OSA) is increasingly associated with insulin resistance. The
underlying pathophysiology remains unclear but intermittent hypoxia (IH)-mediated …
underlying pathophysiology remains unclear but intermittent hypoxia (IH)-mediated …
Whole blood hypoxia-related gene expression reveals novel pathways to obstructive sleep apnea in humans
JC Perry, C Guindalini, L Bittencourt, S Garbuio… - Respiratory Physiology …, 2013 - Elsevier
In this study, our goal was to identify the key genes that are associated with obstructive sleep
apnea (OSA). Thirty-five volunteers underwent full in-lab polysomnography and, according …
apnea (OSA). Thirty-five volunteers underwent full in-lab polysomnography and, according …
Intermittent hypoxia and cognitive function: implications from chronic animal models
BW Row - Hypoxia and tHe circulation, 2007 - Springer
Obstructive sleep apnea syndrome (OSAS) is a frequent sleep disorder in which the upper
airway collapses repeatedly during sleep, resulting in intermittent hypoxia (IH) and asphyxia …
airway collapses repeatedly during sleep, resulting in intermittent hypoxia (IH) and asphyxia …
[HTML][HTML] Experimental models to study end-organ morbidity in sleep apnea: lessons learned and future directions
R Farré, I Almendros, MÁ Martínez-García… - International Journal of …, 2022 - mdpi.com
Sleep apnea (SA) is a very prevalent sleep breathing disorder mainly characterized by
intermittent hypoxemia and sleep fragmentation, with ensuing systemic inflammation …
intermittent hypoxemia and sleep fragmentation, with ensuing systemic inflammation …