[HTML][HTML] Intermittent hypoxia causes histological kidney damage and increases growth factor expression in a mouse model of obstructive sleep apnea
Epidemiological studies demonstrate an association between obstructive sleep apnea
(OSA) and accelerated loss of kidney function. It is unclear whether the decline in function is …
(OSA) and accelerated loss of kidney function. It is unclear whether the decline in function is …
Intermittent hypoxia, respiratory plasticity and sleep apnea in humans: present knowledge and future investigations
JH Mateika, Z Syed - Respiratory physiology & neurobiology, 2013 - Elsevier
This review examines the role that respiratory plasticity has in the maintenance of breathing
stability during sleep in individuals with sleep apnea. The initial portion of the review …
stability during sleep in individuals with sleep apnea. The initial portion of the review …
[HTML][HTML] Identifying pathways modulating sleep duration: from genomics to transcriptomics
KV Allebrandt, M Teder-Laving, P Cusumano… - Scientific reports, 2017 - nature.com
Recognizing that insights into the modulation of sleep duration can emerge by exploring the
functional relationships among genes, we used this strategy to explore the genome-wide …
functional relationships among genes, we used this strategy to explore the genome-wide …
Intermittent hypoxia initiated plasticity in humans: a multipronged therapeutic approach to treat sleep apnea and overlapping co-morbidities
JH Mateika, D Komnenov - Experimental neurology, 2017 - Elsevier
Over the past three decades exposure to intermittent hypoxia (IH) has generally been
considered a stimulus associated with a number of detrimental outcomes. However, there is …
considered a stimulus associated with a number of detrimental outcomes. However, there is …
Sleep apnea research in animals. Past, present, and future
Obstructive sleep apnea (OSA) is a common disorder that describes recurrent collapse of
the upper airway during sleep. Animal models have been pivotal to the understanding of …
the upper airway during sleep. Animal models have been pivotal to the understanding of …
Intermittent hypoxia and sleep-disordered breathing: current concepts and perspectives
P Lévy, JL Pépin, C Arnaud, R Tamisier… - European …, 2008 - Eur Respiratory Soc
There are three major types of sleep-disordered breathing (SDB) with respect to prevalence
and health consequences, ie obstructive sleep apnoea syndrome (OSAS), Cheyne–Stokes …
and health consequences, ie obstructive sleep apnoea syndrome (OSAS), Cheyne–Stokes …
[HTML][HTML] A novel chip for cyclic stretch and intermittent hypoxia cell exposures mimicking obstructive sleep apnea
Intermittent hypoxia (IH), a hallmark of obstructive sleep apnea (OSA), plays a critical role in
the pathogenesis of OSA-associated morbidities, especially in the cardiovascular and …
the pathogenesis of OSA-associated morbidities, especially in the cardiovascular and …
The protective role of SOD1 overexpression in central mediation of bradycardia following chronic intermittent hypoxia in mice
J Chen, H Gu, RD Wurster… - American Journal of …, 2021 - journals.physiology.org
Obstructive sleep apnea (OSA) is a highly prevalent sleep disorder that is associated with
many cardiovascular complications. Similar to OSA, chronic intermittent hypoxia (CIH)(a …
many cardiovascular complications. Similar to OSA, chronic intermittent hypoxia (CIH)(a …
Genome-wide gene expression profiling in children with non-obese obstructive sleep apnea
A Khalyfa, OS Capdevila, MO Buazza, LD Serpero… - Sleep medicine, 2009 - Elsevier
BACKGROUND: Obstructive sleep apnea (OSA) is a multi-factorial and highly prevalent
disorder in which both genetic and environmental factors may be involved. If left untreated …
disorder in which both genetic and environmental factors may be involved. If left untreated …
[HTML][HTML] Obstructive Sleep Apnea-Associated Intermittent Hypoxia-Induced Immune Responses in Males, Pregnancies, and Offspring
Obstructive sleep apnea (OSA), a respiratory sleep disorder associated with cardiovascular
diseases, is more prevalent in men. However, OSA occurrence in pregnant women rises to a …
diseases, is more prevalent in men. However, OSA occurrence in pregnant women rises to a …