Recurrent CMV retinitis in a non-HIV patient with drug-resistant CMV

QV Hoang, DM Simon, GN Kumar, F Oh… - Graefe's Archive for …, 2010 - Springer
Background We report a case of recurrent cytomegalovirus (CMV) retinitis in an HIV-
negative patient with CD4+ T lymphocytopenia. Methods Case report. Results A 41-year-old …

Treatment of cytomegalovirus retinitis with an intraocular sustained-release ganciclovir implant: a randomized controlled clinical trial

DF Martin, DJ Parks, SD Mellow, FL Ferris… - Archives of …, 1994 - jamanetwork.com
Background and Methods: We performed a randomized controlled clinical trial to assess the
safety and efficacy of a 1 μg/h ganciclovir implant for the treatment of newly diagnosed …

Progression rates of cytomegalovirus retinopathy in ganciclovir-treated and untreated patients

GN Holland, JD Shuler - Archives of Ophthalmology, 1992 - jamanetwork.com
• Cytomegalovirus retinopathy lesions in patients with the acquired immunodeficiency
syndrome may continue to enlarge despite ganciclovir sodium treatment. In an historical …

Comparison of cytomegalovirus (CMV) UL97 gene sequences in the blood and vitreous of patients with acquired immunodeficiency syndrome and CMV retinitis

H Hu, DA Jabs, MS Forman, BK Martin… - The Journal of …, 2002 - academic.oup.com
Cytomegalovirus (CMV) resistance to ganciclovir occurs via mutations in the UL97 gene.
CMV DNA, from vitreous and blood specimens and from culture isolates from 87 patients …

Initial experience with an eight-month sustained-release intravitreal ganciclovir implant for the treatment of CMV retinitis associated with AIDS

JS Duker, M Robinson, R Anand… - … Surgery, Lasers and …, 1995 - journals.healio.com
* BACKGROUND AND OBJECTIVE: An intravitreal device administering ganciclovir in a
sustained-release fashion has been developed for site-specific therapy of cytomegalovirus …

Progressive disease due to ganciclovir-resistant cytomegalovirus in immunocompromised patients

A Erice, S Chou, KK Biron, SC Stanat… - … England Journal of …, 1989 - Mass Medical Soc
CYTOMEGALOVIRUS (CMV) infections are a major cause of morbidity and mortality among
immunocompromised patients, especially recipients of bone marrow and solid-organ …

Replacing ganciclovir implants

MG Morley, JS Duker, P Ashton, MR Robinson - Ophthalmology, 1995 - Elsevier
Purpose: The authors report their surgical experience replacing empty ganciclovir implants
in patients with acquired immune deficiency syndrome (AIDS)-related cytomegalovirus …

Loss of cytomegalovirus (CMV) viraemia following highly active antiretroviral therapy in the absence of specific anti-CMV therapy

J Deayton, A Mocroft, P Wilson, VC Emery… - Aids, 1999 - journals.lww.com
Objective: To determine the effect of highly active antiretroviral therapy (HAART) on
cytomegalovirus (CMV) viraemia and retinitis in patients at high risk of disease. Design …

Efficacy and tolerance of intravitreal ganciclovir in cytomegalovirus retinitis in acquired immune deficiency syndrome

I Cochereau-Massin, P Lehoang, M Lautier-Frau… - Ophthalmology, 1991 - Elsevier
Forty-four patients with acquired immune deficiency syndrome with cytomegalovirus (CMV)
retinitis (64 eyes) intolerant of or refusing systemic antiviral therapy received 710 intravitreal …

A safety study of oral valganciclovir maintenance treatment of cytomegalovirus retinitis

J Lalezari, J Lindley, S Walmsley… - JAIDS Journal of …, 2002 - journals.lww.com
Valganciclovir, an oral prodrug of the anti-cytomegalovirus (CMV) agent ganciclovir, was
evaluated in a single-arm open-label safety study. AIDS patients (median CD4 lymphocyte …