Inhaled corticosteroids and survival in chronic obstructive pulmonary disease: does the dose matter?

DD Sin, SFP Man - European Respiratory Journal, 2003 - Eur Respiratory Soc
Recent data suggest that inhaled corticosteroids reduce the number of clinical
exacerbations in chronic obstructive pulmonary disease (COPD). It remains unknown …

Inhaled corticosteroids in COPD: friend or foe?

A Agusti, LM Fabbri, D Singh, J Vestbo… - European …, 2018 - Eur Respiratory Soc
The efficacy, safety and positioning of inhaled corticosteroids (ICS) in the treatment of
patients with chronic obstructive pulmonary disease (COPD) is much debated, since it can …

An overview of the benefits and drawbacks of inhaled corticosteroids in chronic obstructive pulmonary disease

S Singh, YK Loke - International journal of chronic obstructive …, 2010 - Taylor & Francis
Background The benefit harm profile of inhaled corticosteroids, and their effect on patient
oriented outcomes and comorbid pneumonia, osteoporosis and cardiovascular disease in …

Inhaled corticosteroids in patients with stable chronic obstructive pulmonary disease: a systematic review and meta-analysis

MB Drummond, EC Dasenbrook, MW Pitz, DJ Murphy… - Jama, 2008 - jamanetwork.com
Context Recent studies of inhaled corticosteroid (ICS) therapy for managing stable chronic
obstructive pulmonary disease (COPD) have yielded conflicting results regarding survival …

Inhaled corticosteroids and the risk of a first exacerbation in COPD patients

MN De Melo, P Ernst, S Suissa - European Respiratory Journal, 2004 - Eur Respiratory Soc
The role of inhaled corticosteroids (ICS) in asthma is well established, but their benefit in the
management of chronic obstructive pulmonary disease (COPD) is still controversial. The …

Risk-to-benefit ratio of inhaled corticosteroids in patients with COPD

D Price, B Yawn, G Brusselle, A Rossi - Primary Care Respiratory …, 2013 - nature.com
While the pharmacological management of chronic obstructive pulmonary disease (COPD)
has evolved from the drugs used to treat asthma, the treatment models are different and the …

Airway inflammation in COPD after long-term withdrawal of inhaled corticosteroids

LIZ Kunz, NHT Ten Hacken… - European …, 2017 - Eur Respiratory Soc
Long-term treatment with inhaled corticosteroids (ICS) might attenuate lung function decline
and decrease airway inflammation in a subset of patients with chronic obstructive pulmonary …

Withdrawal of inhaled corticosteroids can be safe in COPD patients at low risk of exacerbation: a real-life study on the appropriateness of treatment in moderate COPD …

A Rossi, M Guerriero, A Corrado - Respiratory research, 2014 - Springer
Background It has been suggested that withdrawal of inhaled corticosteroids (ICS) in COPD
patients on maintenance treatment results in deterioration of symptoms, lung function and …

Inhaled corticosteroids for stable chronic obstructive pulmonary disease

IA Yang, MS Clarke, EHA Sim… - Cochrane Database of …, 2012 - cochranelibrary.com
Background The role of inhaled corticosteroids (ICS) in chronic obstructive pulmonary
disease (COPD) has been the subject of much controversy. Major international guidelines …

Withdrawal of inhaled corticosteroids in individuals with COPD-a systematic review and comment on trial methodology

NJ Nadeem, SJC Taylor, SM Eldridge - Respiratory research, 2011 - Springer
Inhaled corticosteroids (ICS) reduce COPD exacerbation frequency and slow decline in
health related quality of life but have little effect on lung function, do not reduce mortality, and …