Coupling between clathrin-coated-pit invagination, cortactin recruitment, and membrane scission observed in live cells
CJ Merrifield, D Perrais, D Zenisek - Cell, 2005 - cell.com
During clathrin-mediated endocytosis, membrane scission marks the isolation of a cargo-
laden clathrin-coated pit (CCP) from the cell exterior. Here we used live-cell imaging of a pH …
laden clathrin-coated pit (CCP) from the cell exterior. Here we used live-cell imaging of a pH …
Quantifying the dynamic interactions between a clathrin-coated pit and cargo molecules
AV Weigel, MM Tamkun… - Proceedings of the …, 2013 - National Acad Sciences
Clathrin-mediated endocytosis takes place through the recruitment of cargo molecules into a
growing clathrin-coated pit (CCP). Despite the importance of this process to all mammalian …
growing clathrin-coated pit (CCP). Despite the importance of this process to all mammalian …
Cargo and dynamin regulate clathrin-coated pit maturation
Total internal reflection fluorescence microscopy (TIR-FM) has become a powerful tool for
studying clathrin-mediated endocytosis. However, due to difficulties in tracking and …
studying clathrin-mediated endocytosis. However, due to difficulties in tracking and …
Evolving models for assembling and shaping clathrin-coated pits
Clathrin-mediated endocytosis occurs via the assembly of clathrin-coated pits (CCPs) that
invaginate and pinch off to form clathrin-coated vesicles (CCVs). It is well known that adaptor …
invaginate and pinch off to form clathrin-coated vesicles (CCVs). It is well known that adaptor …
Flat clathrin lattices: stable features of the plasma membrane
Clathrin-mediated endocytosis (CME) is a fundamental property of eukaryotic cells.
Classical CME proceeds via the formation of clathrin-coated pits (CCPs) at the plasma …
Classical CME proceeds via the formation of clathrin-coated pits (CCPs) at the plasma …
Understanding living clathrin‐coated pits
JZ Rappoport, SM Simon, A Benmerah - Traffic, 2004 - Wiley Online Library
Most knowledge of clathrin‐mediated endocytosis has been gained by biochemical
fractionation and in vitro assays. Recently, the study of endocytosis has extended into the …
fractionation and in vitro assays. Recently, the study of endocytosis has extended into the …
Endocytic accessory proteins are functionally distinguished by their differential effects on the maturation of clathrin-coated pits
Diverse cargo molecules (ie, receptors and ligand/receptor complexes) are taken into the
cell by clathrin-mediated endocytosis (CME) utilizing a core machinery consisting of cargo …
cell by clathrin-mediated endocytosis (CME) utilizing a core machinery consisting of cargo …
Morphological changes of plasma membrane and protein assembly during clathrin-mediated endocytosis
A Yoshida, N Sakai, Y Uekusa, Y Imaoka, Y Itagaki… - PLoS …, 2018 - journals.plos.org
Clathrin-mediated endocytosis (CME) proceeds through a series of morphological changes
of the plasma membrane induced by a number of protein components. Although the …
of the plasma membrane induced by a number of protein components. Although the …
Cargo regulates clathrin-coated pit dynamics
MA Puthenveedu, M von Zastrow - Cell, 2006 - cell.com
Clathrin-coated pits (CCPs) are generally considered a uniform population of endocytic
machines containing mixed constitutive and regulated membrane cargo. Contrary to this …
machines containing mixed constitutive and regulated membrane cargo. Contrary to this …
Local clustering of transferrin receptors promotes clathrin-coated pit initiation
Clathrin-mediated endocytosis (CME) is the major pathway for concentrative uptake of
receptors and receptor–ligand complexes (cargo). Although constitutively internalized …
receptors and receptor–ligand complexes (cargo). Although constitutively internalized …