Role of human papillomavirus in penile carcinomas worldwide

L Alemany, A Cubilla, G Halec, E Kasamatsu, B Quirós… - European urology, 2016 - Elsevier
Background Invasive penile cancer is a rare disease with an approximately 22 000 cases
per year. The incidence is higher in less developed countries, where penile cancer can …

Human papillomavirus infection and immunohistochemical p16INK4a expression as predictors of outcome in penile squamous cell carcinomas

SM Bezerra, A Chaux, MW Ball, SF Faraj, E Munari… - Human pathology, 2015 - Elsevier
Approximately 50% of penile squamous cell carcinomas (SCC) are associated with high-risk
human papillomavirus (HR-HPV) infection. We evaluated the correlation of p16 INK4a …

Prevalence of human papillomavirus and implication on survival in Chinese penile cancer

C Chu, K Chen, X Tan, J Lu, Y Yang, YJ Zhang, K Yao… - Virchows Archiv, 2020 - Springer
We assessed the prevalence of HPV DNA in a large series of Chinese penile cancer and
examine its association with the histological subtype, p16 INK4a expression, and prognosis …

Report from the International Society of Urological Pathology (ISUP) Consultation Conference on Molecular Pathology of Urogenital Cancers V: Recommendations on …

S Canete-Portillo, EF Velazquez… - The American Journal …, 2020 - journals.lww.com
Penile cancer and its precursor lesions are morphologically and clinically heterogenous and
they can be further characterized by immunohistochemical (IHC) and molecular genetic …

[HTML][HTML] The role of histologic subtype, p16INK4a expression, and presence of human papillomavirus DNA in penile squamous cell carcinoma

J Steinestel, A Al Ghazal, A Arndt, TJ Schnoeller… - BMC cancer, 2015 - Springer
Background Up to 50% of penile squamous cell carcinomas (pSCC) develop in the context
of high-risk human papillomavirus (HR-HPV) infection. Most of these tumours have been …

Value of p16INK4a in the pathology of invasive penile squamous cell carcinomas: a report of 202 cases

AL Cubilla, B Lloveras, M Alejo, O Clavero… - The American journal …, 2011 - journals.lww.com
Background One third to one half of penile squamous cell carcinomas (SCCs) are related to
human papillomavirus (HPV) infection. Viral detection is usually carried out by polymerase …

[HTML][HTML] The dual pathogenesis of penile neoplasia: The heterogeneous morphology of human papillomavirus-related tumors

A Chaux, DF Sanchez, MJ Fernández-Nestosa… - Asian Journal of …, 2022 - Elsevier
Objective Penile neoplasia, usually of squamous histogenesis, is currently classified into
human papillomavirus (HPV)-related or-dependent and non-HPV-related or-independent …

Human papillomavirus prevalence and type distribution in penile carcinoma

C Miralles-Guri, L Bruni, AL Cubilla… - Journal of clinical …, 2009 - jcp.bmj.com
Background: Penile carcinoma is an uncommon and potentially mutilating disease with a
heterogeneous aetiology. Several risk factors have been established for its development …

Histologic classification of penile intraepithelial neoplasia

EF Velazquez, A Chaux, AL Cubilla - Seminars in diagnostic pathology, 2012 - Elsevier
Penile squamous cell carcinomas (SCCs) and their corresponding precancerous lesions
can be classified in 2 major groups: human papillomavirus (HPV) related and HPV …

Clinical significance of p53 and p16ink4a status in a contemporary North American Penile Carcinoma Cohort

K Zargar-Shoshtari, PE Spiess, AE Berglund… - Clinical genitourinary …, 2016 - Elsevier
Background Because of the low incidence of penile carcinoma (PC), the value of p16 ink4a,
p53, and human papilloma virus (HPV) infection status in clinical practice remains unclear …