Head and neck cancer: from anatomy to biology

P Bose, NT Brockton, JC Dort - International journal of cancer, 2013 - Wiley Online Library
The 20th century saw great advances in anatomy‐based (surgery and radiotherapy) and
chemotherapy approaches for treating head and neck squamous cell carcinoma (HNSCC) …

[HTML][HTML] Overview of current and future biologically based targeted therapies in head and neck squamous cell carcinoma

A Matta, R Ralhan - Head & neck oncology, 2009 - Springer
Recent advances in genomics, proteomics, bioinformatics and systems biology have
unraveled the complex aberrant signaling networks in cancer. The knowledge accrued has …

[HTML][HTML] Clinical update on head and neck cancer: molecular biology and ongoing challenges

E Alsahafi, K Begg, I Amelio, N Raulf, P Lucarelli… - Cell death & …, 2019 - nature.com
Head and neck squamous cell carcinomas (HNSCCs) are an aggressive, genetically
complex and difficult to treat group of cancers. In lieu of truly effective targeted therapies …

Targeting cellular and molecular drivers of head and neck squamous cell carcinoma: current options and emerging perspectives

S Ausoni, P Boscolo-Rizzo, B Singh… - Cancer and Metastasis …, 2016 - Springer
Despite improvements in functional outcomes attributable to advances in radiotherapy,
chemotherapy, surgical techniques, and imaging techniques, survival in head and neck …

[HTML][HTML] Targeted therapy for head and neck cancer: signaling pathways and clinical studies

Q Li, Y Tie, A Alu, X Ma, H Shi - Signal transduction and targeted …, 2023 - nature.com
Head and neck cancer (HNC) is malignant, genetically complex and difficult to treat and is
the sixth most frequent cancer, with tobacco, alcohol and human papillomavirus being major …

Head and neck cancer: Current challenges and future perspectives

GR Bhat, RG Hyole, J Li - Advances in Cancer Research, 2021 - Elsevier
Head and neck cancers are a heterogeneous, aggressive and genetically complex
collection of malignancies of the oral cavity, nasopharynx, oropharynx, hypopharynx, larynx …

[HTML][HTML] Clinical update on cancer: molecular oncology of head and neck cancer

Y Suh, I Amelio, T Guerrero Urbano, M Tavassoli - Cell death & disease, 2014 - nature.com
Head and neck cancers encompass a heterogeneous group of tumours that, in general, are
biologically aggressive in nature. These cancers remain difficult to treat and treatment can …

Molecular aspects of head and neck cancer therapy

SV Puram, JW Rocco - Hematology/Oncology Clinics, 2015 - hemonc.theclinics.com
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Promising new molecular targeted therapies in head and neck cancer

K Dorsey, M Agulnik - Drugs, 2013 - Springer
Despite advances in multimodality therapies for the treatment of squamous cell carcinoma of
the head and neck (SCCHN), survival rates, functional outcomes and toxicities of therapy …

Targeted therapy in head and neck cancer

SK Kundu, M Nestor - Tumor Biology, 2012 - Springer
Head and neck squamous cell carcinoma (HNSCC) of multi-factorial etiopathogenesis is
rising worldwide. Treatment-associated toxicity problems and treatment failure in advanced …