Blood vessel remodeling is crucial in tumor growth. Growth factors released by tumor cells
and endothelium-extracellular matrix interactions are highlighted in tumor angiogenesis …

Tumor angiogenesis is critical to tumor growth and metastasis, yet much is unknown about
the role vascular cells play in the tumor microenvironment. In vitro models that mimic in vivo …

Angiogenesis marks the transformation of a benign local tumor into a life‐threatening
disease. Many in vitro assays are available on two‐dimensional (2D) platforms, however …

Tumor angiogenesis plays a central role in the development and metastasis of
hepatocellular carcinoma. Cancer cells secrete angiogenic factors to recruit vascular …

Hepatocellular carcinoma (HCC) progression is closely related to pathological fibrosis,
which involves heterotypic intercellular interactions (HIIs) between liver cancer cells and …

Hepatocellular carcinoma (HCC) is a densely vascularized tumor that is highly dependent
on angiogenic pathways to direct arterial blood flow to the growing neoplasm, though little is …

Hepatocellular carcinoma (HCC) is the sixth most common cancer and the second leading
cause of cancer worldwide. Despite approvals of several therapeutics to treat advanced …

The tumor microenvironment is closely associated with tumor malignancy, and includes
tumor relapse and metastasis trigged by epithelial‑mesenchymal transition (EMT), which …

Background The recruitment of vascular stromal and endothelial cells is an early event
occurring during cancer cell growth at premetastatic niches, but how the microenvironment …

The tumour microenvironment and tumour angiogenesis play a critical role in the
development and therapy of many cancers, but in vitro models reflecting these …