Chemerin is a novel adipocyte-derived factor inducing insulin resistance in primary human skeletal muscle cells
H Sell, J Laurencikiene, A Taube, K Eckardt… - Diabetes, 2009 - Am Diabetes Assoc
OBJECTIVE Chemerin is an adipokine that affects adipogenesis and glucose homeostasis
in adipocytes and increases with BMI in humans. This study was aimed at investigating the …
in adipocytes and increases with BMI in humans. This study was aimed at investigating the …
Expression of human chemerin induces insulin resistance in the skeletal muscle but does not affect weight, lipid levels, and atherosclerosis in LDL receptor knockout …
M Becker, K Rabe, C Lebherz, J Zugwurst, B Göke… - Diabetes, 2010 - Am Diabetes Assoc
OBJECTIVE Chemerin is a recently discovered hepatoadipokine that regulates adipocyte
differentiation as well as chemotaxis and activation of dendritic cells and macrophages …
differentiation as well as chemotaxis and activation of dendritic cells and macrophages …
Effects of weight loss and exercise on chemerin serum concentrations and adipose tissue expression in human obesity
R Chakaroun, M Raschpichler, N Klöting, A Oberbach… - Metabolism, 2012 - Elsevier
Chemerin is a chemoattractant adipokine that regulates adipogenesis and may induce
insulin resistance. Chemerin serum concentrations are elevated in obese, insulin-resistant …
insulin resistance. Chemerin serum concentrations are elevated in obese, insulin-resistant …
Chemerin exacerbates glucose intolerance in mouse models of obesity and diabetes
Obesity, characterized by an excess of adipose tissue, is an established risk factor for
cardiovascular disease and type 2 diabetes. Different mechanisms linking obesity with these …
cardiovascular disease and type 2 diabetes. Different mechanisms linking obesity with these …
[HTML][HTML] Differential patterns of serum concentration and adipose tissue expression of chemerin in obesity: adipose depot specificity and gender dimorphism
Chemerin, a recognized chemoattractant, is expressed in adipose tissue and plays a role in
adipocytes differentiation and metabolism. Gender-and adipose tissue-specific differences …
adipocytes differentiation and metabolism. Gender-and adipose tissue-specific differences …
Chemerin: a multifaceted adipokine involved in metabolic disorders
Metabolic syndrome is a global public health problem and predisposes individuals to
obesity, diabetes and cardiovascular disease. Although the underlying mechanisms remain …
obesity, diabetes and cardiovascular disease. Although the underlying mechanisms remain …
[HTML][HTML] Chemerin enhances insulin signaling and potentiates insulin-stimulated glucose uptake in 3T3-L1 adipocytes
M Takahashi, Y Takahashi, K Takahashi, FN Zolotaryov… - FEBS letters, 2008 - Elsevier
To explore a novel adipokine, we screened adipocyte differentiation-related gene and found
that TIG2/chemerin was strongly induced during the adipocyte differentiation. Chemerin was …
that TIG2/chemerin was strongly induced during the adipocyte differentiation. Chemerin was …
Chemerin is a novel adipokine associated with obesity and metabolic syndrome
Soluble protein hormones are key regulators of a number of metabolic processes, including
food intake and insulin sensitivity. We have used a signal sequence trap to identify genes …
food intake and insulin sensitivity. We have used a signal sequence trap to identify genes …
Interleukin-1ß induces the novel adipokine chemerin in adipocytes in vitro
S Kralisch, S Weise, G Sommer, J Lipfert, U Lossner… - Regulatory peptides, 2009 - Elsevier
Chemerin has recently been characterized as a novel adipokine playing a crucial role in
adipocyte differentiation and insulin signalling. In the current study, the impact of insulin …
adipocyte differentiation and insulin signalling. In the current study, the impact of insulin …
Serum chemerin levels vary with time of day and are modified by obesity and tumor necrosis factor-α
Chemerin is an adipokine with important regulatory roles in adipogenesis. In humans, serum
total chemerin (ie prochemerin plus chemerin) levels are positively associated with body …
total chemerin (ie prochemerin plus chemerin) levels are positively associated with body …