Objectives Aim of this study was to assess vascular morphology and dimension of the entire
aorta and branch vessels in MFS using thoracoabdominal MR angiography (MRA) …

Background: Marfan syndrome (MFS), an inherited disorder of connective tissue
characterized by abnormalities in the skeletal, ocular, and cardiovascular systems, is caused …

β-Blockers, eg, atenolol, are the cornerstone therapy for thoracic aortic aneurysm (TAA) in
patients with Marfan syndrome; however, continued aortic dilatation has been reported. We …

Background—Marfan syndrome (MFS) is caused by mutations in the fibrillin-1 gene and
dysregulation of transforming growth factor-β (TGF-β). Recent evidence suggests that …

Marfan syndrome (MFS) is a genetic disorder that results in accelerated aortic root widening
and aneurysm. However, management of MFS patients with blood pressure (BP)‐lowering …

Objective Several RCTs have been conducted to assess the efficacy and safety of
angiotensin receptor blocker (ARB) and beta-blocker (BB) therapy for Marfan syndrome …

Background The effect of FBN1 mutation type on the severity of cardiovascular
manifestations in patients with Marfan syndrome (MFS) has been reported with disparity …

Introduction: Marfan syndrome is a multisystemic connective tissue disorder caused mainly
by mutations in the fibrillin-1 gene. The entire cardiovascular system is affected in patients …

Objective—Marfan's syndrome is characterized by the formation of ascending aortic
aneurysms resulting from altered assembly of extracellular matrix microfibrils and chronic …

Background Diseases of the descending aorta have emerged as a clinical issue in Marfan
syndrome following improvements in proximal aorta surgical treatment and the consequent …