Quercetin, a flavonoid, inhibits the proliferation, differentiation, and mineralization of osteoblasts in vitro

M Notoya, Y Tsukamoto, H Nishimura, JT Woo… - European journal of …, 2004 - Elsevier
It is possible that the flavonoids that are found in many foods might have a protective effect
against osteoclastic activity. However, little information is available about the effects of …

Quercetin, a flavonoid, inhibits proliferation and increases osteogenic differentiation in human adipose stromal cells

YJ Kim, YC Bae, KT Suh, JS Jung - Biochemical pharmacology, 2006 - Elsevier
Flavonoids, which have been detected in a variety of foods, have been repeatedly reported
to affect bone metabolism. However, the effects of flavonoids on osteoblastogenesis remain …

Quercetin suppresses bone resorption by inhibiting the differentiation and activation of osteoclasts

JT Woo, H Nakagawa, M Notoya… - Biological and …, 2004 - jstage.jst.go.jp
Although quercetin has suppressed bone resorption in several animal studies, its target cells
and the mechanism of its action related to bone resorption has not been fully elucidated. We …

Modulation of osteoclastogenesis in porcine bone marrow cultures by quercetin and rutin

CM Rassi, M Lieberherr, G Chaumaz, A Pointillart… - Cell and tissue …, 2005 - Springer
Flavonols, in contrast to soybean isoflavones, are the most abundant phytoestrogens in
western diets, being present in onions, beans, fruits, red wine, and tea. They may protect …

Effects of flavonoid on calcium content in femoral tissue culture and parathyroid hormone-stimulated osteoclastogenesis in bone marrow culture in vitro

M Yamaguchi, R Hamamoto, S Uchiyama… - Molecular and cellular …, 2007 - Springer
The effect of various flavonoids, which are present in food and plants, on bone calcium
content and osteoclastogenesis were investigated to compare action of flavonoid on bone …

Potent inhibitory effect of naturally occurring flavonoids quercetin and kaempferol on in vitro osteoclastic bone resorption

A Wattel, S Kamel, R Mentaverri, F Lorget… - Biochemical …, 2003 - Elsevier
Several recent studies have suggested that flavonols, a class of phytochemicals with many
biological activities, might exert a protective effect against post-menopausal bone loss. In the …

Flavonoid quercetin decreases osteoclastic differentiation induced by RANKL via a mechanism involving NFκB and AP‐1

A Wattel, S Kamel, C Prouillet, JP Petit… - Journal of cellular …, 2004 - Wiley Online Library
Flavonoids are micronutrients widely present in food of plant origin. They have been
attributed pharmacological properties such as anticancer and prevention of age‐related …

Assessment of the role of flavonoids for inducing osteoblast differentiation in isolated mouse bone marrow derived mesenchymal stem cells

S Srivastava, R Bankar, P Roy - Phytomedicine, 2013 - Elsevier
Quercetin and rutin are common flavonoids in fruit and vegetables, and have been reported
to affect bone development. However, the effect of flavonoids on osteoblast differentiation …

[HTML][HTML] Effect of quercetin on preosteoblasts and bone defects

RWK Wong, ABM Rabie - The open orthopaedics journal, 2008 - ncbi.nlm.nih.gov
Quercetin is a flavonol, also a phytoestrogen, available commonly in onion and apple. Our
laboratory investigated its effect on MC3T3-E1 cells' alkaline phosphatase activity in vitro …

Quercetin, a bioflavonoid, accelerates TNF-α-induced growth inhibition and apoptosis in MC3T3-E1 osteoblastic cells

YO Son, SH Kook, KC Choi, YS Jang, YM Jeon… - European journal of …, 2006 - Elsevier
The bioflavonoid quercetin is believed to play an important role in preventing bone loss by
affecting osteoclastogenesis and regulating many systemic and local factors including …