The World Health Organization (WHO) has put forth recommendations for the use of
integrase (IN) strand transfer inhibitors (INSTIs) to be part of the first-line combination …

Objectives The most recent guidelines suggest using integrase strand-transfer inhibitors
(InSTIs) as the preferred antiretroviral regimens for naive HIV-infected individuals. However …

Antiretroviral therapy containing an integrase strand transfer inhibitor (INSTI) plus two NRTIs
has become the recommended treatment for antiretroviral-naive HIV-1-infected patients in …

The growing emergence of non-nucleoside reverse transcriptase inhibitor (NNRTI) HIV drug
resistance in sub-Saharan Africa (SSA) led to the World Health Organization (WHO) …

Background: This study aims to delineate the resistance profiles to integrase strand transfer
inhibitors (INSTIs) among patients in southern Taiwan who have experienced antiretroviral …

Background Routine HIV drug resistance genotyping identified an integrase sequence
harbouring T97A, E138K, G140S and Q148H, with high predicted resistance to all integrase …

Objectives This study evaluated the emergence of mutations associated with integrase
strand transfer inhibitors (INSTI) resistance (INSTI-RMs) and the integrase evolution in …

Background HIV treatment guidelines have traditionally recommended that all HIV-positive
individuals are tested for evidence of drug resistance prior to starting ART. Testing for …

Objectives Integrase strand transfer inhibitors (INSTIs) have been recently recommended as
the preferred first-line option for antiretroviral treatment initiators in low-and middle-income …

Objectives The objective of this study was to define the natural genotypic variation of the HIV-
1 integrase gene across Europe for epidemiological surveillance of integrase strand-transfer …