Effect of dolutegravir functional monotherapy on HIV-1 virological response in integrase strand transfer inhibitor resistant patients
LK Naeger, P Harrington, T Komatsu… - Antiviral …, 2016 - journals.sagepub.com
Background VIKING-4 assessed the safety and efficacy of dolutegravir in heavily
antiretroviral treatment-experienced patients who had documented integrase strand transfer …
antiretroviral treatment-experienced patients who had documented integrase strand transfer …
Characterization of HIV-1 integrase gene and resistance associated mutations prior to roll out of integrase inhibitors by Kenyan National HIV-Treatment Program in …
BACKGROUND: Antiretroviral therapy containing an integrase strand transfer inhibitor plus
two Nucleoside Reverse Transcriptase inhibitors has now been recommended for treatment …
two Nucleoside Reverse Transcriptase inhibitors has now been recommended for treatment …
Preliminary report of transmitted drug resistance to integrase strand chain transfer inhibitors in treatment-naïve HIV infected patients
P Ferrer, V Ramos, MI Puente, A Afani - Diagnostic Microbiology and …, 2023 - Elsevier
Transmitted Resistance exists in a newly diagnosed person who has not yet started their
treatment. Our objective was to obtain a profile of HIV-1 resistance to integrase inhibitors in …
treatment. Our objective was to obtain a profile of HIV-1 resistance to integrase inhibitors in …
HIV-1 integrase resistance among highly antiretroviral experienced patients from Morocco
N Alaoui, MA El Alaoui, H El Annaz, FZ Farissi… - Intervirology, 2019 - karger.com
Background: We aimed to analyze for the first time in Morocco the integrase (IN) sequence
variability among highly experienced HIV-1-infected patients with no prior IN strand transfer …
variability among highly experienced HIV-1-infected patients with no prior IN strand transfer …
Emergent drug resistance with integrase strand transfer inhibitor-based regimens
KJ Lepik, PR Harrigan, B Yip, L Wang, MA Robbins… - Aids, 2017 - journals.lww.com
Objectives: To estimate the incidence of and risk factors for emergent resistance to integrase
strand transfer inhibitor (INSTI) and nucleoside (-tide) reverse transcriptase inhibitors (NRTI) …
strand transfer inhibitor (INSTI) and nucleoside (-tide) reverse transcriptase inhibitors (NRTI) …
Analyses of HIV-1 integrase sequences prior to South African national HIV-treatment program and availability of integrase inhibitors in Cape Town, South Africa
HIV-Integrase (IN) has proven to be a viable target for highly specific HIV-1 therapy. We
aimed to characterize the HIV-1 IN gene in a South African context and identify resistance …
aimed to characterize the HIV-1 IN gene in a South African context and identify resistance …
[PDF][PDF] Prevalence and incidence of integrase drug resistance in BC, Canada, 2009-2015
KJ Lepik, B Yip, MA Robbins, C Woods… - … on Retroviruses and …, 2016 - croiconference.org
Background In British Columbia (BC), Canada, use of the integrase inhibitors (INI) in
antiretroviral therapy (ART) regimens has increased rapidly in recent years. The objective of …
antiretroviral therapy (ART) regimens has increased rapidly in recent years. The objective of …
Emergence of resistance in HIV-1 integrase with dolutegravir treatment in a pediatric population from the IMPAACT P1093 study
C Vavro, T Ruel, A Wiznia, N Montañez… - Antimicrobial agents …, 2022 - Am Soc Microbiol
ABSTRACT P1093 is a multicenter, open-label, phase I/II study of pharmacokinetics, safety,
and tolerability of dolutegravir plus an optimized background regimen in pediatric …
and tolerability of dolutegravir plus an optimized background regimen in pediatric …
Analysis of HIV‐1 integrase genotypes and polymorphisms among integrase inhibitors‐based antiretroviral treatment naïve patients in South Sudan
M Giovanetti, S Farcomeni, L Sernicola… - Journal of Medical …, 2022 - Wiley Online Library
HIV‐1 genetic diversity and drug resistance mutations remain public health challenges
especially in regions where treatment is limited. The aim of this study was to characterize the …
especially in regions where treatment is limited. The aim of this study was to characterize the …
HIV-1 integrase resistance associated mutations and the use of dolutegravir in Sub-Saharan Africa: a systematic review and meta-analysis protocol
ENJ Semengue, MM Santoro, VN Ndze, B Dambaya… - Systematic reviews, 2020 - Springer
Abstract Background Sub-Saharan Africa carries the greatest burden of HIV-infection with
increasing drug resistance burden, which requires improved patient management and …
increasing drug resistance burden, which requires improved patient management and …