100 YEARS OF INSULIN: Arresting or curing type 1 diabetes: an elusive goal, but closing the gap

PJ Martens, C Gysemans… - Journal of …, 2021 - joe.bioscientifica.com
Type 1 diabetes is one of the most common chronic diseases in children and adolescents,
but remains unpreventable and incurable. The discovery of insulin, already 100 years ago …

One hundred years of insulin therapy

C Mathieu, PJ Martens… - Nature Reviews …, 2021 - nature.com
At the time of its first clinical application 100 years ago, insulin was presented as the cure for
people with diabetes mellitus. That transpired to be an overstatement, yet insulin has proven …

Type 1 diabetes mellitus: a brave new world

PJ Martens, C Mathieu - Nature Reviews Endocrinology, 2024 - nature.com
One hundred years after the Nobel prize was bestowed on Banting and McLeod for the
'discovery'of insulin, we are again seeing major evolutions in the management of type 1 …

100 years of insulin: celebrating the past, present and future of diabetes therapy

EK Sims, ALJ Carr, RA Oram, LA DiMeglio… - Nature medicine, 2021 - nature.com
The year 2021 marks the centennial of Banting and Best's landmark description of the
discovery of insulin. This discovery and insulin's rapid clinical deployment effectively …

[HTML][HTML] The contributions of insulin to science in medicine

P Kurtzhals, SCL Gough - Diabetic Medicine, 2021 - ncbi.nlm.nih.gov
The discovery of insulin in Toronto in 1921, now 100 years ago, was nothing less than a
miracle. It quite rightly stands out as one of the most significant accomplishments of modern …

Insulins: past, present, and future

CA Borgoño, B Zinman - Endocrinology and Metabolism Clinics, 2012 - endo.theclinics.com
Since its discovery and first clinical use in the 1920s, insulin therapy has revolutionized the
treatment and natural history of both type 1 and type 2 diabetes mellitus. This article …

The promising future of insulin therapy in diabetes mellitus

R Cheng, N Taleb… - American Journal …, 2021 - journals.physiology.org
The first therapeutic use of insulin by Frederick Banting and Charles Best in 1921
revolutionized the management of type 1 diabetes and considerably changed the lives of …

The future of insulin therapy

T Heise - Diabetes Research and Clinical Practice, 2021 - Elsevier
Although insulin therapy was already introduced one-hundred years ago, insulin
formulations are still being refined to reduce the risk of hypoglycaemia and of other insulin …

Insulin therapy in type 2 diabetes: a reflection on the state of the art today, and the potential journeys yet to come

C Sorli - The American Journal of Medicine, 2014 - amjmed.com
It will not be long before we are celebrating the centenary of the clinical use of insulin.
Indeed, it is already more than 100 years since Sir Edward Albert Sharpey-Schafer (in 1910) …

Diabetes Mellitus: A Perspective on the Post-Insulin Era

YC Kudva, KS Nair - Mayo Clinic Proceedings, 2020 - mayoclinicproceedings.org
The year 2021 will mark 100 years since the discovery of insulin. The discovery of insulin
and the start of insulin therapy represent a marvelous multidisciplinary team effort that …