High-grade prostatic intraepithelial neoplasia (PIN) has been accepted as the main
precursor lesion to invasive adenocarcinoma of the prostate, and this is likely to be the case …

High-grade prostatic intraepithelial neoplasia (PIN) is the earliest accepted stage in
carcinogenesis, possessing most of the phenotypic and biochemical changes in cancer …

A better understanding of the early stages of prostate cancer initiation, potentially arising
from precursor lesions, may fuel development of powerful approaches for prostate cancer …

Both the incidence of, and the mortality due to, prostate cancer in the USA are higher in
African-American men than in Caucasian men. This is particularly true in men less than 60 …

High-grade prostatic intraepithelial neoplasia (PIN) is now accepted as the most likely
preinvasive stage of adenocarcinoma, almost two decades after its first formal description …

The search for the precursor of prostatic adenocarcinoma has focused in recent years on the
spectrum of histopathologic changes referred to as high grade prostatic intraepithelial …

High-grade prostatic intraepithelial neoplasia (PIN) is now accepted as the most likely pre-
invasive stage of adenocarcinoma, a decade after its first formal description. PIN has a high …

Bostwick DG & Cheng L (2012) Histopathology 60, 4–27 Precursors of prostate cancer High‐
grade prostatic intraepithelial neoplasia (PIN) is the only accepted precursor of prostatic …

To characterize the molecular feature in prostate carcinogenesis and the putative transition
from prostatic intraepithelial neoplasia (PIN) to invasive prostate cancer (PC), we analyzed …

PURPOSE: Prostatic intraepithelial neoplasia (PIN) is often considered to be a premalignant
lesion and the main precursor of invasive carcinoma of the prostate. We evaluated the …