High grade prostate intraepithelial neoplasia (PIN) is a PSA-independent risk factor for prostate cancer in African American men: results from a pilot study

G Chornokur, G Han, R Tanner, HY Lin, BL Green… - Cancer letters, 2013 - Elsevier
African American men (AAM) demonstrate increased prostate cancer incidence and
mortality rates. We investigated known prostate cancer risk factors in AAM. Prostate specific …

Is prostatic intraepithelial neoplasia in the transition/central zone a true precursor of cancer? A long-term retrospective study in Norway

S Harvei, FJ Skjørten, TE Robsahm, A Berner… - British journal of …, 1998 - nature.com
Prostatic intraepithelial neoplasia (PIN) has been considered as a precursor of prostatic
cancer. Few reports have dealt with the long-term follow-up of PIN lesions, and there is still a …

Mutation profiling indicates high grade prostatic intraepithelial neoplasia as distant precursors of adjacent invasive prostatic adenocarcinoma

SJ Gerrin, AG Sowalsky, SP Balk, H Ye - The Prostate, 2016 - Wiley Online Library
INTRODUCTION High Grade Prostatic Intraepithelial Neoplasia (HGPIN) is the putative
precursor lesion to prostatic adenocarcinoma (PCa), but the precise relationship between …

Prevalence of prostatic intra-epithelial neoplasia (PIN) in biopsies from hospital practice and pilot screening: clinical implications

MR Feneley, JSA Green, MPA Young, P Bose… - Prostate Cancer and …, 1997 - nature.com
As high grade PIN is commonly associated with concomitant cancer, current literature
recommends re-biopsy of patients with high grade PIN. This paper describes the prevalence …

Prostatic intraepithelial neoplasia: its morphological and molecular diagnosis and clinical significance

R Montironi, R Mazzucchelli, A Lopez‐Beltran… - BJU …, 2011 - Wiley Online Library
What's known on the subject? and What does the study add? High grade prostatic
intraepithelial neoplasia (HGPIN) is the precursor lesion to some forms of adenocarcinoma …

Incidence and clinical significance of high-grade prostatic intraepithelial neoplasia in TURP specimens

PB Gaudin, IA Sesterhenn, KJ Wojno, FK Mostofi… - Urology, 1997 - Elsevier
Objectives. To determine the incidence and clinical significance of high-grade prostatic
intraepithelial neoplasia (PIN) in specimens obtained from transurethral resection of the …

Prostatic intraepithelial neoplasia and endocrine manipulation

TH Van der Kwast, F Labrie, B Têtu - European urology, 1999 - karger.com
Prostatic intraepithelial neoplasia (PIN) is the most common precursor lesion of prostatic
adenocarcinoma. In 50-to 70-year-old participants of a randomized screening program for …

Prostatic intraepithelial neoplasia and prostate-specific antigen

JR Porter, MK Brawer - World journal of urology, 1993 - Springer
Prostatic intraepithelial neoplasia (PIN) is a putative premalignant lesion of the prostate
gland. PIN has been demonstrated to share morphologic and phenotypic similarities to …

Prostatic intraepithelial neoplasia: significance and management.

BA Lipski, RL Garcia, MK Brawer - Seminars in urologic oncology, 1996 - europepmc.org
Prostatic intraepthelial neoplasia (PIN) is a putative premalignant change that bears a
morphological similarity to prostatic cancer and shows increased frequency, severity, and …

Cellular and molecular pathology of prostate cancer precursors

CS Foster, DG Bostwick, H Bonkhoff… - … Journal of Urology …, 2000 - Taylor & Francis
Prostate cancer is usually heterogeneous and multifocal, with diverse clinical and
morphologic manifestations. Current understanding of the molecular basis for this …