High-grade prostatic intraepithelial neoplasia is the most likely precursor of prostatic
adenocarcinoma, according to virtually all available evidence. It has a high predictive value …

Many prostate lesions have 'large gland'morphology with gland size similar to or larger than
benign glands, complex glandular architecture including papillary, cribriform, and solid, and …

BACKGROUND High‐grade prostate intraepithelial neoplasia (PIN) is the most likely
precursor of prostate adenocarcinoma. However, the relationship between this lesion and …

OBJECTIVES: Previous work has suggested that prostatic intraepithelial neoplasia (PIN)
may be a premalignant lesion important in tumorigenesis of the prostate. However, to …

High-grade prostatic intraepithelial neoplasia (PIN) is the most likely precursor of prostate
adenocarcinoma, but the frequency and timing of epigenetic changes found in prostate …

High‐grade prostatic intraepithelial neoplasia (HGPIN) is a documented putative precursor
lesion for invasive prostate adenocarcinoma. However, the precise mechanisms of the …

Genetic alterations in primary prostate cancer (CaP) have been extensively studied, yet little
is known about the genetic mechanisms underlying progression of primary CaP to …

The presence and morphology of high-grade prostatic intra-epithelial neoplasia (H-PIN) was
blindly evaluated in 40 totally embedded radical prostatectomy specimens of patients with …

This article reviews various aspects of prostatic intraepithelial neoplasia (PIN). Various
grades of prostatic intraepithelial neoplasia are defined, and terminology is discussed. The …

Isolated high-grade prostatic intraepithelial neoplasia (PIN) has been shown to be a positive
predictor of prostate cancer (PCa) on follow-up biopsy. However, the incidence of isolated …