Treatment of children with congenital cytomegalovirus infection with ganciclovir

MG Michaels, DP Greenberg, DL Sabo… - The Pediatric infectious …, 2003 - journals.lww.com
Background. Congenital cytomegalovirus (CMV) infection affects∼ 1% of live births in the
US. Ten percent of these infants have symptoms at birth and another 10 to 15% acquire …

Treatment of symptomatic congenital cytomegalovirus infection with intravenous ganciclovir followed by long-term oral valganciclovir

J Amir, DG Wolf, I Levy - European journal of pediatrics, 2010 - Springer
Congenital cytomegalovirus infection is the most common cause of nonhereditary
sensorineural hearing loss and an important cause of psychomotor retardation. Earlier …

Ganciclovir therapy for congenital cytomegalovirus infection in six infants

N Tanaka-Kitajima, N Sugaya, T Futatani… - The Pediatric …, 2005 - journals.lww.com
Background: Congenital cytomegalovirus (CMV) infection is common, and its morbidity rate
is high. Ganciclovir (GCV) treatment has been used for congenital CMV infection, but there …

Ganciclovir treatment of symptomatic congenital cytomegalovirus infection: results of a phase II study

RJ Whitley, G Cloud, W Gruber… - Journal of Infectious …, 1997 - academic.oup.com
Congenital cytomegalovirus (CMV) infection occurs in∼ 1% of newborns in the United
States. A phase II evaluation was done of ganciclovir for the treatment of symptomatic …

Ganciclovir therapy for symptomatic congenital cytomegalovirus infection in infants: a two-regimen experience

G Nigro, H Scholz, U Bartmann - The Journal of pediatrics, 1994 - Elsevier
The efficacy of two regimens of ganciclovir therapy was evaluated in 12 infants with
symptomatic congenital cytomegalovirus (CMV) infection. Virologic investigations included …

Selecting neonates with congenital cytomegalovirus infection for ganciclovir therapy

K Smets, K De Coen, I Dhooge, L Standaert… - European journal of …, 2006 - Springer
Objective The objective of this study is to look for evidence based or scientific guidelines for
selection of newborns with congenital cytomegalovirus (CMV) infection that might benefit …

Progressive, long-term hearing loss in congenital CMV disease after ganciclovir therapy

TM Lanzieri, AC Caviness, P Blum… - Journal of the …, 2022 - academic.oup.com
Background Long-term hearing outcomes among children with symptomatic congenital
cytomegalovirus (CMV) disease who received 6-week ganciclovir therapy early in life are …

Antiviral therapy of congenital cytomegalovirus infection

MR Schleiss - Seminars in Pediatric Infectious Diseases, 2005 - Elsevier
Congenital infection caused by human cytomegalovirus (CMV) is a common occurrence, but
its significance is underappreciated. In the developed world, congenital CMV infection …

Neurodevelopmental outcomes following ganciclovir therapy in symptomatic congenital cytomegalovirus infections involving the central nervous system

SE Oliver, GA Cloud, PJ Sánchez, GJ Demmler… - Journal of Clinical …, 2009 - Elsevier
BACKGROUND: Ganciclovir protects against hearing deterioration in infants with
symptomatic congenital cytomegalovirus (CMV) disease involving the central nervous …

Ganciclovir for the treatment of congenital cytomegalovirus: what are the side effects?

A Gwee, N Curtis, TG Connell, S Garland… - The Pediatric …, 2014 - journals.lww.com
Congenital cytomegalovirus (CMV) infection can cause significant neurologic morbidity.
Studies have shown that antiviral therapy with ganciclovir (GCV) or valganciclovir (V-GCV) …