Involvement of NADPH oxidase and iNOS in rodent pulmonary cytokine responses to urban air and mineral particles

R Becher, A Bucht, J Øvrevik, JK Hongslo… - Inhalation …, 2007 - Taylor & Francis
We have investigated the potential of two complex mineral particles (feldspar and mylonite),
quartz (Min-U-Sil), and suspended particulate matter (SRM-1648)(SPM) from urban air to …

[HTML][HTML] NF-κB dependent and independent mechanisms of quartz-induced proinflammatory activation of lung epithelial cells

D van Berlo, AM Knaapen, FJ van Schooten… - Particle and fibre …, 2010 - Springer
In the initiation and progression of pulmonary inflammation, macrophages have classically
been considered as a crucial cell type. However, evidence for the role of epithelial type II …

Rat lung inflammatory responses after in vivo and in vitro exposure to various stone particles

R Becher, RB Hetland, M Refsnes, JE Dahl… - Inhalation …, 2001 - Taylor & Francis
Rat lung alveolar macrophages and type 2 cells were exposed for 20 h in vitro to various
stone particles with differing contents of metals and minerals (a type of mylonite, gabbro …

[HTML][HTML] The pro-inflammatory effects of combined exposure to diesel exhaust particles and mineral particles in human bronchial epithelial cells

VS Grytting, P Chand, M Låg, J Øvrevik… - Particle and Fibre …, 2022 - Springer
Background People are exposed to ambient particulate matter (PM) from multiple sources
simultaneously in both environmental and occupational settings. However, combinatory …

Murine pulmonary inflammatory responses following instillation of size-fractionated ambient particulate matter

CAJ Dick, P Singh, M Daniels, P Evansky… - Journal of toxicology …, 2003 - Taylor & Francis
The mechanisms for increased cardiopulmonary disease in individuals exposed to
particulate air pollution are associated with fine and ultrafine particles that have a high …

Regulation of cytokine production in human alveolar macrophages and airway epithelial cells in response to ambient air pollution particles: further mechanistic studies

S Becker, S Mundandhara, RB Devlin… - Toxicology and applied …, 2005 - Elsevier
In order to better understand how ambient air particulate matter (PM) affect lung health, the
two main airway cell types likely to interact with inhaled particles, alveolar macrophages …

Differential effects of mineral dusts on the in vitro activation of alveolar macrophage eicosanoid and cytokine release

KE Driscoll, JM Higgins, MJ Leytart, LL Crosby - Toxicology in vitro, 1990 - Elsevier
We investigated the in vitro effects of the pneumotoxic agents, silica and asbestos, and the
relatively innocuous materials, aluminium oxide (Al 2 O 3) and titanium dioxide (TiO 2), on …

Lung exposure to mineral dusts enhances the capacity of lung inflammatory cells to release superoxide

A Cantin, F Dubois, R Bégin - Journal of Leucocyte Biology, 1988 - academic.oup.com
In vitro exposure of macrophages and neutrophils to inorganic dusts can enhance their
oxidative metabolism, however the effects of inorganic dust inhalation on lung-inflammatory …

Repeated exposures to roadside particulate matter extracts suppresses pulmonary defense mechanisms, resulting in lipid and protein oxidative damage

M Pardo, Z Porat, A Rudich, JJ Schauer… - Environmental Pollution, 2016 - Elsevier
Exposure to particulate matter (PM) pollution in cities and urban canyons can be harmful to
the exposed population. However, the underlying mechanisms that lead to health effects are …

[HTML][HTML] Respirable stone particles differ in their ability to induce cytotoxicity and pro-inflammatory responses in cell models of the human airways

VS Grytting, M Refsnes, J Øvrevik, MS Halle… - Particle and fibre …, 2021 - Springer
Background Respirable stone-and mineral particles may be a major constituent in
occupational and ambient air pollution and represent a possible health hazard. However …