Multiple sclerosis (MS) is an inflammatory demyelinating disease of the central nervous
system (CNS) where immunopathology is thought to be mediated by myelin-reactive CD4+ T …

Multiple sclerosis (MS), an autoimmune neurological disorder, is driven by self-reactive T
helper (Th) cells. Research on the role of Th17 lymphocytes in MS pathogenesis has made …

It has been firmly established that IL-23 polarized TH17 cells are potent effectors in the
pathogenesis of experimental autoimmune encephalitomyelitis (EAE). However, the relative …

The discovery of the T helper (Th) 17 lineage, involved in the protection against fungal and
extracellular bacterial infections, has profoundly revolutionized our current understanding of …

Recently published studies in multiple sclerosis (MS) and experimental autoimmune
encephalomyelitis (EAE) have demonstrated an association between the development of …

Multiple sclerosis (MS) and its animal model, experimental autoimmune encephalomyelitis
(EAE), are autoimmune demyelinating diseases of the central nervous system (CNS) …

Multiple sclerosis is a T cell-mediated demyelinating disease of the central nervous system.
Interleukin-17-producing T helper cells, named Th17 cells, represent a novel CD4+ T cell …

Multiple sclerosis (MS) is the most important autoimmune disease of the central nervous
system (CNS). Its animal model experimental autoimmune encephalomyelitis (EAE) has …

Multiple sclerosis (MS) is an autoimmune disease characterized by recurrent episodes of
demyelination and axonal lesion mediated by CD4+ T cells with a proinflammatory Th1 and …

Abstract T helper 17 (Th17), a distinct subset of CD4+ T cells with IL-17 as their major
cytokine, orchestrate the pathogenesis of inflammatory and autoimmune diseases …