Systematic studies of mouse embryo culture beginning in 1949 led to an understanding of
essential medium components for early mammalian embryos, and embryo culture from the …

Mammalian preimplantation embryos normally develop within the protected environment of
the female reproductive tract, which virtually precludes studies on embryogenesis in situ …

Human preimplantation embryos were first cultured from the zygote to the sixteen cell stage
by Edwards et al.(1970). Later, human zygotes were cultured in vitro to the blastocyst stage …

Considerable advances in media development for the culture of preimplantation mammalian
embryos have been made since mouse embryos were first cultured and successfully …

There are several treatises on the composition of embryo culture media and the role of
specific medium components in supporting mammalian embryo development in vitro (1–3). It …

The first culture media designed specifically to support development of the preimplantation
mouse embryo were formulated over 50 years ago and were based on balanced salt …

Methods for the culture of preimplantation human embryos evolved primarily from those
used for mouse embryos. The initial method was usually culture in a single medium in …

The culture of human preimplantation embryos from the 1-cell to the morula/blastocyst stage
of development is not satisfactory at present. The success of various IVF laboratories ranges …

A comparison was made of the development of human zygotes in either a one-step (Global®
medium) or two-step culture system (Quinn's Advantage®). A total of 257 normally fertilized …

Several culture medium formulations are now available for the successful production and
propagation of viable human embryos. In the most popular format, nutrients are provided in …