[HTML][HTML] The role of NLRP3 inflammasome in Alzheimer's disease and potential therapeutic targets
T Liang, Y Zhang, S Wu, Q Chen, L Wang - Frontiers in Pharmacology, 2022 - frontiersin.org
Alzheimer's disease (AD) is a common age-related neurodegenerative disease
characterized by progressive cognitive dysfunction and behavioral impairment. The typical …
characterized by progressive cognitive dysfunction and behavioral impairment. The typical …
The involvement of NLRP3 inflammasome in the treatment of Alzheimer's disease
YS Feng, ZX Tan, LY Wu, F Dong, F Zhang - Ageing research reviews, 2020 - Elsevier
Alzheimer's disease (AD) is one of the most common neurodegenerative diseases, and it is
characterised by progressive deterioration in cognitive and memory abilities, which can …
characterised by progressive deterioration in cognitive and memory abilities, which can …
Mechanistic and therapeutic role of NLRP3 inflammasome in the pathogenesis of Alzheimer's disease
D Jha, ENTP Bakker, R Kumar - Journal of neurochemistry, 2023 - Wiley Online Library
Abstract Alzheimer's disease (AD), a progressive neurodegenerative disorder, has emerged
as the most common form of dementia in the elderly. Several pathological hallmarks have …
as the most common form of dementia in the elderly. Several pathological hallmarks have …
Mechanisms of NLRP3 inflammasome activation: its role in the treatment of Alzheimer's disease
Y Zhang, Y Zhao, J Zhang, G Yang - Neurochemical Research, 2020 - Springer
Alzheimer's disease (AD) is a common neurodegenerative disease of progressive dementia
which is characterized pathologically by extracellular neuritic plaques containing …
which is characterized pathologically by extracellular neuritic plaques containing …
[HTML][HTML] Key mechanisms and potential targets of the NLRP3 inflammasome in neurodegenerative diseases
Y Guan, F Han - Frontiers in Integrative Neuroscience, 2020 - frontiersin.org
Neurodegenerative diseases are neuronal disorders characterized by the loss of a large
number of neurons in the human brain. Innate immunity-mediated neuroinflammation …
number of neurons in the human brain. Innate immunity-mediated neuroinflammation …
The NLRP3 inflammasome in Alzheimer's disease
MS Tan, JT Yu, T Jiang, XC Zhu, L Tan - Molecular neurobiology, 2013 - Springer
Innate immunity and inflammatory response plays an important role in the pathogenesis of
Alzheimer's disease (AD). As the major resident immune cells in the brain, microglial cells …
Alzheimer's disease (AD). As the major resident immune cells in the brain, microglial cells …
[HTML][HTML] Targeting NLRP3-mediated neuroinflammation in Alzheimer's disease treatment
J Barczuk, N Siwecka, W Lusa… - International Journal of …, 2022 - mdpi.com
Alzheimer's disease (AD) is the most common cause of dementia in the general population
and, to date, constitutes a major therapeutic challenge. In the pathogenesis of AD …
and, to date, constitutes a major therapeutic challenge. In the pathogenesis of AD …
The role of neuronal NLRP1 inflammasome in Alzheimer's disease: bringing neurons into the neuroinflammation game
The innate immune system and inflammatory response in the brain have critical impacts on
the pathogenesis of many neurodegenerative diseases including Alzheimer's disease (AD) …
the pathogenesis of many neurodegenerative diseases including Alzheimer's disease (AD) …
[HTML][HTML] The involvement of NLRP3 inflammasome in the treatment of neurodegenerative diseases
YS Feng, ZX Tan, LY Wu, F Dong, F Zhang - Biomedicine & …, 2021 - Elsevier
In an ageing society, neurodegenerative diseases have attracted attention because of their
high incidence worldwide. Despite extensive research, there is a lack of conclusive insights …
high incidence worldwide. Despite extensive research, there is a lack of conclusive insights …
[HTML][HTML] Activation of NLRP3 inflammasome and onset of Alzheimer's disease
H Bai, Q Zhang - Frontiers in immunology, 2021 - frontiersin.org
The nucleotide-binding domain leucine-rich repeat and pyrin domain containing receptor
protein 3 (NLRP3) is an important pattern recognition receptor in human innate immunity …
protein 3 (NLRP3) is an important pattern recognition receptor in human innate immunity …