Background: Prospective data on incidence, characteristics, and risk factors for cryptococcal
meningitis immune reconstitution inflammatory syndrome (CM-IRIS) are lacking. Methods …

Abstract Background. Cryptococcal meningitis (CM)-related immune reconstitution
inflammatory syndrome (IRIS) complicates antiretroviral therapy (ART) in 20%–40% of ART …

Objective: HIV-infected patients with treated cryptococcal meningitis are at risk for further
neurological deterioration after commencing combination antiretroviral therapy (cART) …

Background. Human immunodeficiency virus (HIV)-associated cryptococcal meningitis (CM)
is characterized by high fungal burden and limited leukocyte trafficking to cerebrospinal fluid …

Background. Cryptococcal meningitis (CM) is a leading cause of death in individuals
infected with human immunodeficiency virus (HIV). Identifying factors associated with …

Background. Cryptococcosis-associated immune reconstitution inflammatory syndrome (C-
IRIS) may be driven by aberrant T-cell responses against cryptococci. We investigated this in …

Background Although antiretroviral therapy (ART) improves survival in persons with
cryptococcal meningitis (CM) and AIDS, ART frequently elicits HIV immune reconstitution …

Background Initiation of antiretroviral therapy (ART) in human immunodeficiency virus (HIV)-
infected individuals with cryptococcal meningitis places them at risk for Cryptococcus …

A prospective multicenter study of cryptococcal immune reconstitution inflammatory
syndrome (IRIS) was conducted as a substudy of the Bacteriology and Mycology Study …

Background. Cryptococcal meningitis (CM) in South Africa is often treated with fluconazole
as initial therapy. Surveillance data suggest that the prevalence of fluconazole-resistant CM …