Polymorphisms in CYP3A genes, such as CYP3A5} and CYP3A4, as well as in the MDR1
gene, which encodes for P-glycoprotein, have been implicated as genetic markers in several …

The goal of this study was to detect genotypic differences between Spaniards and other
related populations regarding CYP3A4* 1B, CYP3A5* 3, and ABCB1 (MDR1) C3435T …

Polymorphisms in cytochrome P450 CYP3A4 and multidrug resistance (MDR) 1 genes
coding for the important drugmetabolising CYP3A4 and the ATP-binding cassette (ABC) …

The aim of this study was to detect genotypic differences between three populations of
healthy volunteers from Northern Spain (204 subjects), Nicaragua (120 subjects), and El …

CYP3A4, CYP3A5 and MDRâ•’1 Variant Alleles in The Dutch Caucasian Population Page 1
CLINICAL PHARMACOLOGY & TH ERAPEUTICS P42 American Society Cbr Clinical …

The prevalent CYP3A5* 3 and the functional multi-drug resistance gene (MDR1) C3435T
show marked interethnic variation among Orientals, Caucasians and Africans. This study …

Background: It is well recognized that different patients respond in different ways to
medications. The inter-individual variations are greater than the intera-individual variations …

Objectives Mexico harbours a very complex genetically diverse population composed of two
main groups: Mexican Mestizos and at least 68 heterogeneous native Mexican populations …

This study was designed to investigate the potential differences between Spaniards and
Ecuadorian Mestizo people regarding CYP2A6* 1A, CYP2A6* 1B1, CYP2A6* 1x2A …

Aims: Polymorphisms in the CYP2C9 and CYP2C19 genes confer potential risk for specific
adverse drug reactions and therapeutic effect failure. Their frequencies differ among ethnic …