Determination of minor impurities in terazosin hydrochloride by high-performance liquid chromatography

JF Bauer, SK Krogh, ZL Chang, CF Wong - Journal of Chromatography A, 1993 - Elsevier
Minor impurities in the anti-hypertensive agent terazosin monohydrochloride dihydrate were
determined using high-performance liquid chromatography. Manufacturing impurities and …

Improved high-performance liquid chromatographic analysis of terazosin in human plasma

PY Cheah, KH Yuen, ML Liong - Journal of Chromatography B: Biomedical …, 2000 - Elsevier
A simple, sensitive and reproducible high-performance liquid chromatography (HPLC)
method was developed for the determination of terazosin in human plasma. The method …

[引用][C] High-performance liquid chromatographic measurement of prazosin and terazosin in biological fluids

RK Bhamra, RJ Flanagan, DW Holt - Journal of Chromatography B …, 1986 - Elsevier
Prazosin is an orally effective post-sympathetic selective al adrenoceptor antagonist widely
used in the treatment of hypertension and congestive heart failure [l]. Terazosin has close …

Determination of terazosin in human plasma, using high-performance liquid chromatography with fluorescence detection

EC Sekhar, TRK Rao, KR Sekhar, MUR Naidu… - … of Chromatography B …, 1998 - Elsevier
A selective, sensitive, rapid and reproducible high-performance liquid chromatographic
method for the determination of terazosin in plasma is described. The structurally related …

[引用][C] Rapid and sensitive analysis of terazosin in plasma, peritoneal dialysis solution, and urine using high-performance liquid chromatography with fluorescence …

SE Patterson - Journal of Chromatography B: Biomedical Sciences …, 1984 - Elsevier
Terazosin hydrochloride dihydrate (THD) and prazosin hydrochloride (PH), the internal
standard, were obtained from Abbott Labs.(North Chicago, IL, USA). Peritoneal dialysis …

High-performance liquid chromatographic analysis and pharmacokinetics of terazosin in healthy volunteers.

BC Kang, CQ Yang, JE Rhee, OK Suh… - … in molecular pathology …, 2001 - europepmc.org
A high-performance liquid chromatographic (HPLC) analysis of terazosin in 1 ml of human
plasma was developed using prazosin as an internal standard. The plasma sample was …

Efficacy and safety of intravenous terazosin in hypertensive patients: a preliminary report

A Cohen - The American Journal of Medicine, 1986 - Elsevier
Abstract Single intravenous doses of 1, 2, and 5 mg of terazosin and placebo were
administered in a randomized, double-blind, crossover fashion to 12 hypertensive adult …

Effect of age and dose on the incidence of adverse events in the treatment of hypertension in patients receiving terazosin

BS Hosmane, CJ Maurath, DC Jordan… - The Journal of Clinical …, 1992 - Wiley Online Library
Selected adverse events were evaluated from the combined randomized placebo‐controlled
clinical trials (once‐a‐day or twice‐a‐day; monotherapy or combination therapy) of terazosin …

Updating the European Pharmacopoeia impurity profiling method for terazosin and suggesting alternative columns

D Enesei, I Kapui, S Fekete, R Kormány - Journal of pharmaceutical and …, 2020 - Elsevier
This work was motivated by the demand of European Directorate for the Quality of Medicines
and HealthCare (EDQM). A new liquid chromatographic (LC) method was developed for …

Experience with terazosin administered in combination with other antihypertensive agents

SG Chrysant - The American Journal of Medicine, 1986 - Elsevier
In a randomized, double-blind, placebo-controlled, multicenter trial, the efficacy and safety of
terazosin in combination with other antihypertensive agents were assessed using patients …