CURRENT CONCEPTS of hemostasis and thrombosis emphasize the endothelial cell as a
regulatory interface between blood and tissues. 1., 2., 3. The endothelium constitutes an …

The endothelium is intact but activated and dysfunctioning during the early phase of
atherogenesis. Owing to increased endothelial permeability, many blood-derived …

The role of hemostatic factors as predictors of coronary heart disease (CHD) and total
mortality is poorly understood. Therefore, we carried out a prospective cohort study in …

After many years of neglect, the role of thrombosis in myocardial infarction is being
reassessed. It is increasingly clear that all aspects of the haemostatic system are involved …

Occlusive vascular disease most often results from thrombosis superimposed on
atherosclerotic plaque. Disruption of plaque exposes thrombogenic substances within the …

The importance of the haemostatic system in predisposing to or precipitating coronary heart
disease has gained increasing recognition. Major advances have been made in our …

Associations between increased plasma concentrations of the three haemostatic factors—
fibrinogen, Factor VII and plasminogen activator inhibitor 1 (PAI-1)—and cardiovascular …

Background The relation between atherosclerosis and thrombosis has been recognized for
over a century. Until very recently, however, this pathophysiological association has been …

In this paper are reported the basal results of a multidisciplinary, multicenter study designed
to explore in a population with ischemic disease the relation between hemostatic variables …

In 1977, Macfarlane [1] proposed that Ôthrombosis is hemostasis in the wrong placeÕ, and
since then pathological studies, clinical studies, and meta-analyses of randomized trials of …