Depletion of CD4+ T cells during immunization with nonviable Listeria monocytogenes causes enhanced CD8+ T cell-mediated protection against listeriosis

M Kursar, A Köhler, SHE Kaufmann… - The Journal of …, 2004 - journals.aai.org
Immunization of mice with nonviable Listeria monocytogenes generates an insufficient
CD8+ T cell response and consequently only limited protection against subsequent L …

IL-10 regulates memory T cell development and the balance between Th1 and follicular Th cell responses during an acute viral infection

Y Tian, SB Mollo, LE Harrington… - The Journal of …, 2016 - journals.aai.org
T cells provide protective immunity against infections by differentiating into effector cells that
contribute to rapid pathogen control and by forming memory populations that survive over …

A Critical Role for Interleukin 18 in Primary and Memory Effector Responses to Listeria monocytogenes That Extends Beyond Its Effects on Interferon γ Production

M Neighbors, X Xu, FJ Barrat, SR Ruuls… - The Journal of …, 2001 - rupress.org
The stimulation of interferon (IFN)-γ by interleukin (IL)-12 has been shown to provide
protection from intracellular pathogens such as Listeria monocytogenes. Tumor necrosis …

Tissue-level regulation of Th1 and Th2 primary and memory CD4 T cells in response to Listeria infection

AL Marzo, V Vezys, K Williams, DF Tough… - The Journal of …, 2002 - journals.aai.org
Abstract Ag-specific Th1 and Th2 cytokine-producing CD4 T cells were quantitated in
secondary lymphoid and tertiary tissues following oral Listeria monocytogenes infection …

IL-10 directly suppresses CD4 but not CD8 T cell effector and memory responses following acute viral infection

DG Brooks, KB Walsh, H Elsaesser… - Proceedings of the …, 2010 - National Acad Sciences
Mounting effective T cell responses is critical for eliciting long-lasting immunity following viral
infection and vaccination. A multitude of inhibitory and stimulatory factors are induced …

Upregulated IL-7 receptor α expression on colitogenic memory CD4+ T cells may participate in the development and persistence of chronic colitis

T Shinohara, Y Nemoto, T Kanai… - The Journal of …, 2011 - journals.aai.org
We have previously demonstrated that IL-7 is essential for the persistence of colitis as a
survival factor of colitogenic IL-7Rα–expressing memory CD4+ T cells. Because IL-7Rα is …

Production of IL-10 by CD4+ regulatory T cells during the resolution of infection promotes the maturation of memory CD8+ T cells

BJ Laidlaw, W Cui, RA Amezquita, SM Gray… - Nature …, 2015 - nature.com
Memory CD8+ T cells are critical for host defense upon reexposure to intracellular
pathogens. We found that interleukin 10 (IL-10) derived from CD4+ regulatory T cells (Treg …

Listeria monocytogenes infection overcomes the requirement for CD40 ligand in exogenous antigen presentation to CD8+ T cells

SE Hamilton, AR Tvinnereim, JT Harty - The Journal of Immunology, 2001 - journals.aai.org
In vivo priming of CD8+ T lymphocytes against exogenously processed model Ags requires
CD4+ T cell help, specifically interactions between CD40 ligand (CD40L) expressed by …

Treatment with anti-interleukin-10 monoclonal antibody enhances early resistance to but impairs complete clearance of Listeria monocytogenes infection in mice

RD Wagner, NM Maroushek, JF Brown… - Infection and …, 1994 - Am Soc Microbiol
Mice that received an anti-interleukin-10 (anti-IL-10) neutralizing monoclonal antibody
(MAb)(SXC-1) prior to infection with Listeria monocytogenes initially demonstrated …

Innate immune activation of CD4 T cells in salmonella-infected mice is dependent on IL-18

A Srinivasan, RM Salazar-Gonzalez… - The Journal of …, 2007 - journals.aai.org
Production of IFN-γ by CD4 T cells is generally thought to be mediated by TCR triggering,
however, Ag-nonspecific activation of effector CD8 T cells has been reported in infection …