Anomalous venous blood flow and iron deposition in multiple sclerosis

AV Singh, P Zamboni - Journal of Cerebral Blood Flow & …, 2009 - journals.sagepub.com
Multiple sclerosis (MS) is primarily an autoimmune disorder of unknown origin. This review
focuses iron overload and oxidative stress as surrounding cause that leads to …

Normal CSF ferritin levels in MS suggest against etiologic role of chronic venous insufficiency

V Worthington, J Killestein, MJ Eikelenboom… - Neurology, 2010 - AAN Enterprises
Objectives: Chronic cerebrospinal venous insufficiency (CCSVI) has been suggested to be a
possible cause of multiple sclerosis (MS). If the presumed mechanism of venous stasis …

[PDF][PDF] Chronic cerebrospinal venous insufficiency and iron deposition on susceptibility-weighted imaging in patients with multiple sclerosis: a pilot case-control study

R Zivadinov, C Schirda, MG Dwyer, ME Haacke… - Int Angiol, 2010 - researchgate.net
Aim. Chronic cerebrospinal venous insufficiency (CCSVI) is a vascular phenomenon
recently described in multiple sclerosis (MS) that is characterized by stenoses affecting the …

The value of cerebral Doppler venous haemodynamics in the assessment of multiple sclerosis

P Zamboni, E Menegatti, R Galeotti… - Journal of the …, 2009 - Elsevier
Iron stores in the white and deep grey matter in course of multiple sclerosis (MS) have never
been explained and could be related to abnormalities in venous drainage, but this possibility …

Iron stores and cerebral veins in MS studied by susceptibility weighted imaging

EM Haacke, J Garbern, Y Miao, C Habib… - International …, 2010 - search.proquest.com
AIM: In this paper, we seek to determine whether the iron deposition as seen by
susceptibility weighted imaging (SWI) in the basal ganglia and thalamus of patients with …

Use of MR venography for characterization of the extracranial venous system in patients with multiple sclerosis and healthy control subjects

R Zivadinov, A Lopez-Soriano, B Weinstock-Guttman… - Radiology, 2011 - pubs.rsna.org
Purpose To investigate the differences in the extracranial venous system in patients with
multiple sclerosis (MS) and healthy control (HC) subjects by using magnetic resonance (MR) …

No association of abnormal cranial venous drainage with multiple sclerosis: a magnetic resonance venography and flow-quantification study

MP Wattjes, BW Van Oosten, WL De Graaf… - Journal of Neurology …, 2011 - jnnp.bmj.com
Background Recent studies using colour-coded Doppler sonography showed that chronic
impaired venous drainage from the central nervous system is almost exclusively found in …

No evidence of chronic cerebrospinal venous insufficiency at multiple sclerosis onset

C Baracchini, P Perini, M Calabrese… - Annals of …, 2011 - Wiley Online Library
Objective An impaired cerebrospinal venous drainage, defined as chronic cerebrospinal
venous insufficiency (CCSVI), has been recently hypothesized to be the possible cause of …

Decreased brain venous vasculature visibility on susceptibility-weighted imaging venography in patients with multiple sclerosis is related to chronic cerebrospinal …

R Zivadinov, GU Poloni, K Marr, CV Schirda… - BMC neurology, 2011 - Springer
Background The potential pathogenesis between the presence and severity of chronic
cerebrospinal venous insufficiency (CCSVI) and its relation to clinical and imaging outcomes …

[PDF][PDF] Hemodynamic patterns of chronic cerebrospinal venous insufficiency in multiple sclerosis. Correlation with symptoms at onset and clinical course

I Bartolomei, F Salvi, R Galeotti, E Salviato… - Int Angiol, 2010 - researchgate.net
Aim. Chronic cerebrospinal venous insufficiency (CCSVI) is associated with multiple
sclerosis (MS). CCSVI is detected by transcranial and extracranial color-Doppler …