The duration of withdrawal affects the muscarinic signaling in the nucleus accumbens after chronic morphine exposure in neonatal rats
X Jiang, JJ Zhang, S Song, Y Li… - Journal of …, 2021 - journals.physiology.org
The infants experience withdrawal from opiates, and time-dependent adaptations in
neuronal activity of nucleus accumbens (NAc) may be crucial for this process. A key …
neuronal activity of nucleus accumbens (NAc) may be crucial for this process. A key …
Muscarinic and nicotinic presynaptic modulation of EPSCs in the nucleus accumbens during postnatal development
L Zhang, RA Warren - Journal of neurophysiology, 2002 - journals.physiology.org
We have studied the modulatory effects of cholinergic agonists on excitatory postsynaptic
currents (EPSCs) in nucleus accumbens (nAcb) neurons during postnatal development …
currents (EPSCs) in nucleus accumbens (nAcb) neurons during postnatal development …
Repeated morphine exposure decreased the nucleus accumbens excitability during short‐term withdrawal
LJ Heng, J Yang, YH Liu, WT Wang, SJ Hu, GD Gao - Synapse, 2008 - Wiley Online Library
It is well known that the nucleus accumbens plays an important role in drug reinforcing effect
and relapse. However, the cellular neuroadaptations that take place in accumbens neurons …
and relapse. However, the cellular neuroadaptations that take place in accumbens neurons …
Potentiation of synaptic strength and intrinsic excitability in the nucleus accumbens after 10 days of morphine withdrawal
X Wu, M Shi, C Wei, M Yang, Y Liu, Z Liu… - Journal of …, 2012 - Wiley Online Library
Neuroadaptations in the nucleus accumbens (NAc) are associated with the development of
drug addiction. Plasticity in synaptic strength and intrinsic excitability of NAc medium spiny …
drug addiction. Plasticity in synaptic strength and intrinsic excitability of NAc medium spiny …
[HTML][HTML] Acute morphine alters GABAergic transmission in the central amygdala during naloxone-precipitated morphine withdrawal: role of cyclic AMP
M Bajo, SG Madamba, M Roberto… - Frontiers in integrative …, 2014 - frontiersin.org
The central amygdala (CeA) plays an important role in opioid addiction. Therefore, we
examined the effects of naloxone-precipitated morphine withdrawal (WD) on GABAergic …
examined the effects of naloxone-precipitated morphine withdrawal (WD) on GABAergic …
Intermittent morphine treatment induces a long‐lasting increase in cholinergic modulation of GABAergic synapses in nucleus accumbens of adult rats
M De Rover, JC Lodder, ANM Schoffelmeer… - Synapse, 2005 - Wiley Online Library
Repeated exposure to drugs of abuse causes persistent behavioral sensitization and
associated adaptations of striatal neurotransmission, which is thought to play an important …
associated adaptations of striatal neurotransmission, which is thought to play an important …
Antagonism of mGlu2/3 receptors in the nucleus accumbens prevents oxytocin from reducing cued methamphetamine seeking in male and female rats
A Bernheim, KC Leong, C Berini, CM Reichel - … Biochemistry and Behavior, 2017 - Elsevier
Methamphetamine (meth) addiction is a prevalent health concern worldwide, yet remains
without approved pharmacological treatments. Preclinical evidence suggests that oxytocin …
without approved pharmacological treatments. Preclinical evidence suggests that oxytocin …
Decreased myelin-related gene expression in the nucleus accumbens during spontaneous neonatal opioid withdrawal in the absence of long-term behavioral effects …
KN Borrelli, KK Wingfield, EJ Yao, CA Zamorano… - …, 2023 - Elsevier
Prenatal opioid exposure is a major health concern in the United States, with the incidence
of neonatal opioid withdrawal syndrome (NOWS) escalating in recent years. NOWS occurs …
of neonatal opioid withdrawal syndrome (NOWS) escalating in recent years. NOWS occurs …
Delayed extinction and stronger drug-primed reinstatement of methamphetamine seeking in rats prenatally exposed to morphine
YL Shen, ST Chen, TY Chan, TW Hung, PL Tao… - Neurobiology of learning …, 2016 - Elsevier
Prenatal morphine (PM) affects the development of brain reward system and cognitive
function. The present study aimed to determine whether PM exposure increases the …
function. The present study aimed to determine whether PM exposure increases the …
Downregulation of mGluR2/3 receptors during morphine withdrawal in rats impairs mGluR2/3-and NMDA receptor-dependent long-term depression in the nucleus …
Z Qian, X Wu, Y Qiao, M Shi, Z Liu, W Ren, J Han… - Neuroscience …, 2019 - Elsevier
Drugs of abuse modify synaptic long-term potentiation and long-term depression (LTD) in
the nucleus accumbens, and the impairment of synaptic plasticity in this brain region may be …
the nucleus accumbens, and the impairment of synaptic plasticity in this brain region may be …