Relapse is a major problem in treating methamphetamine use disorder.“Incubation of
craving” during abstinence is a rat model for persistence of vulnerability to craving and …

The key problem for the treatment of drug addiction is relapse to drug use after abstinence
that can be triggered by drug‐associated cues, re‐exposure to the drug itself and stress …

One of the most challenging issues in the treatment of substance use disorder, including
misuse of opioids such as oxycodone, is persistent vulnerability to relapse, often triggered …

Numerous findings confirm that the metabotropic glutamate receptors (mGluRs) are involved
in the conditioned place preference (CPP) induced by morphine. Here we focused on the …

Morphine exposure during the neonatal period can promote changes in pain signaling
pathways that can be expressed as an increased nociceptive response in adult life …

Here, we investigate the effects of obesity induced by monosodium glutamate (MSG) on
cognitive impairment and whether this model induces any alteration in the affinity, density …

Addiction to the psychostimulant Methamphetamine (METH) is characterised by high rates of
relapse. Currently there are no approved effective pharmacotherapies for METH …

Adaptive changes in brain areas following drug withdrawal are believed to contribute to drug
seeking and relapse. Cocaine withdrawal alters the expression of GluR1 and GluR2/3 …

Rationale: Treatment of developing rat pups with morphine (MOR) causes the development
of physical dependence, but the relationship of the withdrawal syndrome to the …

Prenatal exposure to drugs of abuse often leads to physiological and neurobiological
abnormalities including decreased brain and body weight, cognitive deficits and behavioral …