Adolescence represents a distinctive vulnerable period when exposure to stressful
situations including opioid exposure can entail lasting effects on brain and can change …

Understanding the neurobiological underpinnings of abstinence from drugs of abuse is
critical to allow better recovery and ensure relapse prevention in addicted subjects. By …

Purpose. Sevoflurane, one of the most used general anesthetics, is widely used in clinical
practice all over the world. Previous studies indicated that sevoflurane could induce neuron …

Aim: Glutamatergic neurotransmission in the nucleus accumbens (NAc) is crucial for the
relapse to heroin seeking. The aim of this study was to determine whether mGluR5 in the …

We investigated possible alterations of pharmacologically‐isolated, evoked GABAA
inhibitory postsynaptic potentials (eIPSPs) and miniature GABAA inhibitory postsynaptic …

Administration of monosodium glutamate (MSG) to neonatal rats has been reportedto
destroy aspartatergic (ASPergic) and glutamatergic (GLUergic) neurons. Ageing has been …

In abstinent opiate addicts, relapse can be triggered by exposure to environmental cues
associated with drug use; thus, the disruption of these learned associations may be an …

Introduction: Morphine withdrawal syndrome is mediated via several central and peripheral
neurological pathways. In the present study we investigated the role of N-methyl-D aspartic …

There is a growing concern related to the use of opioid maintenance treatment during
pregnancy. Studies in both humans and animals have reported reduced cognitive …

Opioid addiction is one of the most crucial issues in the world. Opioid abuse by parents
makes children more prone to many psychological disorders such as drug addiction …