Family genetic studies, suicide, and suicidal behavior

DA Brent, JJ Mann - American Journal of Medical Genetics Part …, 2005 - Wiley Online Library
The extant adoption, twin, and family studies of suicide and suicidal behavior are reviewed.
Suicidal behavior is highly familial, and on the basis of twin and adoption studies, heritable …

Familial transmission of suicidal behavior

DA Brent, N Melhem - Psychiatric Clinics of North America, 2008 - Elsevier
Adoption and twin studies show that familial transmission of suicidal behavior is partly
attributable to genetic factors. Transmission of suicidal behavior is mediated by transmission …

Familial pathways to early-onset suicide attempt: risk for suicidal behavior in offspring of mood-disordered suicide attempters

DA Brent, M Oquendo, B Birmaher… - Archives of general …, 2002 - jamanetwork.com
Background Although adoption, twin, and family studies have shown that suicidal behavior
is familial, the risk factors for familial transmission from parent to child remain unclear …

Familial transmission of suicidal ideation and suicide attempts: evidence from a general population sample

RD Goodwin, AL Beautrais, DM Fergusson - Psychiatry research, 2004 - Elsevier
The goals of the study were (1) to determine the association between parental and offspring
suicidal ideation and suicide attempts among adult offspring in a general community …

Genetics and suicidal behavior

A Roy - Risk Factors for Youth Suicide, 2013 - api.taylorfrancis.com
There are five lines of evidence about genetic factors in suicide. This paper will review the
clinical, twin, Iowa-500, Amish, and Copenhagen adoption studies, all of which provide …

Suicidal behavior runs in families: a controlled family study of adolescent suicide victims

DA Brent, J Bridge, BA Johnson… - Archives of general …, 1996 - jamanetwork.com
Background: While previous studies have shown an increased rate of suicidal behavior in
the relatives of suicide victims, it is unclear if this is attributable merely to increased familial …

Genetics of suicide: an overview

RJ Baldessarini, J Hennen - Harvard review of psychiatry, 2004 - journals.lww.com
Risk for suicide may have heritable contributions. Evidence supporting this hypothesis
includes strong and consistent findings from more than 20 controlled family studies …

Peripubertal suicide attempts in offspring of suicide attempters with siblings concordant for suicidal behavior

DA Brent, M Oquendo, B Birmaher… - American Journal of …, 2003 - Am Psychiatric Assoc
OBJECTIVE: The authors sought to determine 1) whether the risk for familial transmission of
suicidal behavior is greater with increased family loading for suicide attempts, and 2) …

Familial pathways to early-onset suicidal behavior: familial and individual antecedents of suicidal behavior

NM Melhem, DA Brent, M Ziegler… - American Journal of …, 2007 - Am Psychiatric Assoc
Objective: The authors sought to identify clinical predictors of new-onset suicidal behavior in
children of parents with a history of mood disorder and suicidal behavior. Method: In a …

What can psychiatric genetics offer suicidology?

P McGuffin, A Marušič, A Farmer - Crisis: The Journal of Crisis …, 2001 - psycnet.apa.org
There is good evidence from recent studies that depression is familial, and that a substantial
proportion of the variation in liability is explained by genes. Suicidal behavior, including …