Introduction: In the early seventies chemotherapy significantly improved survival in
osteosarcoma. Since then minor innovations have occurred although recent years have …

Introduction: Although chemotherapy is currently indispensable for the treatment of
osteosarcoma, chemotherapy for this rare cancer has not been developed based on …

Osteosarcoma is the most common primary tumor of bone. Approximately 2/3 of patients
who present with localized osteosarcoma can be expected to be cured of their disease with …

Opinion statement Improving cure rates for osteosarcoma continues to be a major challenge.
The clinical management of individual patients is exacting and requires a skilled …

Osteosarcoma, the most common type of primary malignant tumour that develops in bone,
can be classified into several different sub-types. While the majority of osteosarcomas are …

Introduction: Current treatment of osteosarcoma includes surgical resection of all gross
disease in conjunction with systemic chemotherapy to control micro-metastatic disease. This …

Despite significant advancements in the diagnosis and treatment of osteosarcoma to date,
overall survival has remained relatively constant for over 2 decades. The challenge in …

This paper reviews the contribution of chemotherapy in the conquest of osteosarcoma. It
discusses how the treatment of osteosarcoma has evolved over the last five decades …

Introduction: Osteosarcoma (OS), the most common primary malignant bone tumor, is
currently treated with pre-and postoperative chemotherapy in association with the surgical …

Background: We designed the study to investigate whether methotrexate, doxorubicin, and
cisplatinum (MAP) chemotherapy strategy was still the preferred option for the survival of …