Abstract Surfactant protein-D (SP-D) participates in the innate response to inhaled
microorganisms and organic antigens, and contributes to immune and inflammatory …

Surfactant protein D (SP-D) is a member of the family of collagenous host defense lectins,
designated collectins. There is increasing evidence that SP-D, like SP-A, is an important …

Pulmonary surfactant protein-D (SP-D) is a member of the collectin family of C-type lectins
that is synthesized in many tissues including respiratory epithelial cells in the lung. SP-D is …

Surfactant protein D (SP-D) is a calcium-dependent carbohydrate-binding protein that is
secreted into the pulmonary airspaces by type II epithelial and Clara cells. Previous studies …

Surfactant protein D (SP-D) is believed to contribute to nonimmune host defense within the
alveoli and distal airways of the lung. SP-D molecules can bind to specific carbohydrates on …

Surfactant protein D (SP-D) is considered to play an important role in innate immunity in the
lungs by binding, via its multiple C-type lectin domains, to carbohydrate structures present …

Surfactant, a lipoprotein complex, was originally described for its essential role in reducing
surface tension at the air–liquid interface of the lung; however, it is now recognized as being …

Rapid removal of apoptotic cells is an important mechanism for immune homeostasis and
the resolution of inflammation. Delayed clearance of apoptotic alveolar macrophages may …

Lung surfactant protein-D (SP-D), a collectin mainly produced by alveolar type II cells,
initiates the effector mechanisms of innate immunity on binding to microbial carbohydrates …

▪ Abstract The lung collectins, SP-A and SP-D, are important components of the innate
immune response to microbial challenge and participate in other aspects of immune and …