Proposal of a clinically relevant working classification of pituitary neuroendocrine tumors based on pituitary transcription factors

S Silva-Ortega, A García-Martinez, MN de Jaime… - Human Pathology, 2021 - Elsevier
The immunohistochemistry (IHC) characterization of pituitary transcription factors (PTFs)
PIT1, TPIT, and SF1, which enable the identification of three different adenohypophyseal cell …

Clinical implications of the new WHO classification 2017 for pituitary tumors

W Saeger, A Koch - Experimental and Clinical Endocrinology & …, 2021 - thieme-connect.com
According to the WHO classification 2017 of Pituitary Tumors adenomas are classified not
only by structure and immunostaining for pituitary hormones but also by expression of the …

Pituitary transcription factors in the immunohistochemical and molecular diagnosis of pituitary tumours—a systematic review

IF Burcea, VN Năstase, C Poiană - Endokrynologia Polska, 2021 - journals.viamedica.pl
Introduction: Although histopathology remains in the first line of the diagnosis of pituitary
pathology, immunohistochemistry and molecular biology are currently in charge of providing …

Overview of the 2017 WHO classification of pituitary tumors

O Mete, MB Lopes - Endocrine pathology, 2017 - Springer
This review focuses on discussing the main changes on the upcoming fourth edition of the
WHO Classification of Tumors of the Pituitary Gland emphasizing histopathological and …

How valuable is the RT-qPCR of pituitary-specific transcription factors for identifying pituitary neuroendocrine tumor subtypes according to the new WHO 2017 criteria?

ME Torregrosa-Quesada, A García-Martínez… - Cancers, 2019 - mdpi.com
The classification of pituitary neuroendocrine tumors (PitNETs) subtypes continues
generating interest. In 2017, the World Health Organization (WHO) proposed considering …

Transcription Factor Immunohistochemistry in the Classification of Pituitary Neuroendocrine Tumor/Adenoma: Proposal in a Limited-Resource Setting

R Sood, D Chatterjee, P Dutta… - Archives of Pathology …, 2024 - meridian.allenpress.com
Context.—Pituitary neuroendocrine tumors/adenomas are common intracranial tumors that
require accurate subtyping because each tumor differs in its biologic behavior and response …

Overview of the 2022 WHO classification of pituitary tumors

SL Asa, O Mete, A Perry, RY Osamura - Endocrine pathology, 2022 - Springer
This review summarizes the changes in the 5th Edition of the WHO Classification of
Endocrine and Neuroendocrine Tumors that relate to the pituitary gland. The new …

Histologic features of pituitary adenomas and sellar region masses

BK Kleinschmidt-DeMasters, MBS Lopes - … Surgical Neuropathology: A …, 2018 - Elsevier
This chapter focuses on surgical pathologic features of pituitary adenomas using the new
classification systems that employ transcription factors steroidogenic factor-1 (SF1) and PIT1 …

A standardised diagnostic approach to pituitary neuroendocrine tumours (PitNETs): a European Pituitary Pathology Group (EPPG) proposal

C Villa, A Vasiljevic, ML Jaffrain-Rea, O Ansorge… - Virchows Archiv, 2019 - Springer
Abstract The 2017 World Health Organization (WHO) classification proposes to type and
subtype primary adenohypophyseal tumours according to their cell lineages with the aim to …

Molecular, functional, and histopathological classification of the pituitary neuroendocrine neoplasms

C Inomoto, S Tahara, K Oyama, M Kimura… - Brain Tumor …, 2021 - Springer
In 2017, WHO published an updated classification of the pituitary adenomas according to
the lineages defined by the transcription factors, PIT1, SF1 and TPIT. Nomenclature of the …