Chondroitin 4-sulfate proteoglycan forms an extracellular network in human and rat central nervous system

A Bertolotto, G Rocca, D Schiffer - Journal of the neurological sciences, 1990 - Elsevier
Summary Chondroitin 4-sulfate proteoglycan (C4S-PG) was localized both in rat and human
central nervous system (CNS) by monoclonal and polyclonal antisera recognizing the 4 …

Chondroitin sulfate: a key molecule in the brain matrix

JCF Kwok, P Warren, JW Fawcett - … journal of biochemistry & cell biology, 2012 - Elsevier
Chondroitin sulfate is a glycosaminoglycan composed of N-acetylgalactosamine and
glucuronic acid. It attaches to a core protein to form chondroitin sulfate proteoglycan (CSPG) …

The role of chondroitin sulfate proteoglycans in nervous system development

CP Mencio, RK Hussein, P Yu… - … of Histochemistry & …, 2021 - journals.sagepub.com
The orderly development of the nervous system is characterized by phases of cell
proliferation and differentiation, neural migration, axonal outgrowth and synapse formation …

Chondroitin sulphate proteoglycans: key modulators of spinal cord and brain plasticity

K Bartus, ND James, KD Bosch, EJ Bradbury - Experimental neurology, 2012 - Elsevier
Chondroitin sulphate proteoglycans (CSPGs) are a family of inhibitory extracellular matrix
molecules that are highly expressed during development, where they are involved in …

Chondroitin/dermatan sulfates in the central nervous system: their structures and functions in health and disease

U Rauch, J Kappler - Advances in Pharmacology, 2006 - Elsevier
Publisher Summary The central nervous system (CNS) is a rich and complex source of
proteins modified with chondroitin/dermatan sulfate (CS/DS) chains. During brain …

Chondroitin sulfate proteoglycans: Structure‐function relationship with implication in neural development and brain disorders

S Avram, S Shaposhnikov, C Buiu… - BioMed research …, 2014 - Wiley Online Library
Chondroitin sulfate proteoglycans (CSPGs) are extracellular matrix components that contain
two structural parts with distinct functions: a protein core and glycosaminoglycan (GAG) side …

Heparan sulphate proteoglycans in glia and in the normal and injured CNS: expression of sulphotransferases and changes in sulphation

F Properzi, R Lin, J Kwok, M Naidu… - European Journal of …, 2008 - Wiley Online Library
Heparan sulphate proteoglycans (HSPGs) have multiple functions relevant to the control of
the CNS injury response, particularly in modulating the effects of growth factors and …

[HTML][HTML] Sugar glues for broken neurons

VP Swarup, CP Mencio, V Hlady… - Biomolecular concepts, 2013 - degruyter.com
Proteoglycans (PGs) regulate diverse functions in the central nervous system (CNS) by
interacting with a number of growth factors, matrix proteins, and cell surface molecules …

[HTML][HTML] Chondroitin sulfates and their binding molecules in the central nervous system

L Djerbal, H Lortat-Jacob, JCF Kwok - Glycoconjugate journal, 2017 - Springer
Chondroitin sulfate (CS) is the most abundant glycosaminoglycan (GAG) in the central
nervous system (CNS) matrix. Its sulfation and epimerization patterns give rise to different …

[PDF][PDF] Chondroitin sulfate and neuronal disorders

S Miyata, H Kitagawa - Front Biosci (Landmark Ed), 2016 - article.imrpress.com
The brain extracellular matrix (ECM) is involved in several aspects of neuronal development,
plasticity, and pathophysiology. Chondroitin sulfate proteoglycans (CSPGs), consisting of …