Transthyretin (formerly called prealbumin) plays important physiological roles as a
transporter of thyroxine and retinol-binding protein. X-ray structural studies have provided …

Revised Manuscript Received September 2, 19939 abstract: A recently reported variant of
human transthyretin (TTR), Leu-55-Pro, implicated as the causative agent in early-onset …

Abstract Transthyretin (TTR)(formerly, thyroxine binding prealbumin) is an evolutionarily
conserved serum and cerebrospinal fluid protein that transports holo-retinol-binding protein …

Transthyretin is a tetrameric plasma protein associated with two forms of amyloid disease.
The structure of the highly amyloidogenic transthyretin triple mutant TTRG53S/E54D/L55S …

Wild-type and variant transthyretins form amyloid fibrils in two different diseases. The
biologically active form of transthyretin is a tetramer but there is evidence that a monomeric …

Revised Manuscript Received November 15, 1990 abstract: Transthyretin (TTR) is a plasma
protein interacting with thyroxine T4 and retinol binding protein (RBP). Several variants of …

~ R f~~~ l~ l A~ l O~ VS: TTR= transthyretin; ATTR= familial transthyretin amyloidosis;,. IS=
mass spectrometry; Da= dalton; A h= autonomic neuropathy; CTS= carpal tunnel syndrome; …

Transthyretin is a human protein capable of amyloid formation that is believed to cause
several types of amyloid disease, depending on the sequence deposited. Previous studies …

Transthyretin (TTR) is a soluble human plasma protein that can be converted into amyloid by
acid-mediated dissociation of the homotetramer into monomers. The pH required for …

Transthyretin (TTR) is a 127-amino acid residue transport protein. In plasma, TTR exists as a
tetramer and binds the hormone thyroxine and the retinol-binding protein− vitamin A …